Genmab — Maj 2021

[E_L]

and a bit more on amivantamab https://endpts.com/jj-busts-out-a-small-update-for-its-antibody-tki-combo-in-lung-cancer-whetting-appetites-as-fda-thinks-it-over/

[Bulder]

thx E L. Easier to understand

[E_L]

one more then - Biotech
ASCO: Johnson & Johnson's bispecific lung cancer combo shows promise as Tagrisso backup, but the Big Pharma wants more https://www.fiercebiotech.com/biotech/asco-janssen-s-bispecific-lung-cancer-combo-shows-promise-as-tagrisso-back-up-but-big

[Sukkeralf]

Nice work diggin´ good stuff up

[E_L]

ASCO : A phase 1b, open-label, dose-escalation study to evaluate camidanlumab tesirine (Cami) as monotherapy in patients (pts) with advanced solid tumors. https://meetinglibrary.asco.org/record/196008/abstract

[Bulder]

Well, response not impressive. But dont know what to expect in these indications.

[E_L]

no, maybe we'll hear a bit more in June; this is data from December with only 'Median (range) treatment duration was 22 (1–178) days'

[E_L]

another maintenance abstract - Daratumumab (DARA) maintenance therapy following DARA + cyclophosphamide, bortezomib, and dexamethasone (CyBorD) induction therapy in multiple myeloma (MM): End-of-study analysis of LYRA https://meetinglibrary.asco.org/record/195444/abstract

[E_L]

and one more maintenance on the Auriga trial, Dara vs SOC https://meetinglibrary.asco.org/record/201317/abstract

[Bulder]

I wonder if they'll wait for that study before they file dara as maintenance, or if Cass part 2 is enough.

[Bulder]

Winkel didn't answer that Q, but on the other hand he said "We fully expect a number of new label extensions to be executed in the coming time."

[Bulder]

I assume "a number of" is more than 1.

[E_L]

we'll also see more extensions being requested by other companies , like Amgen for Carfilzomib, just as JNJ included Revlimid in many of the extensions

[E_L]

or like AbbVie for Lemzoparlimab , whatever that is, never heard of it, New trial - https://clinicaltrials.gov/ct2/show/NCT04895410

[E_L]

Daratumumab and Pomalidomide in Previously Treated Patients With AL Amyloidosis (DarPAL) - New trial https://clinicaltrials.gov/ct2/show/NCT04895917

[deleted-user]

Det er en meget lille, men insisterende (!) kø, ved indgangen til Genmab i dag.

[Bulder]

Og de behøver ikke vise coronapas for at komme ind.

[Bulder]

US har helt skiftet farve. NBI mørkegrøn.

[Darvin]

Og - de er ikke mindre glade for Genmab i dag derovre

[AaBforever]

Pt omregnet 2375