Genmab — April 2021
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Corticosteroid Tapering in Patients with Relapsed or Refractory Multiple Myeloma Receiving Subcutaneous Daratumumab http://jhoponline.com/jhop-issue-archive/2021-issues/march-2021-vol-11-special-feature/18873-corticosteroid-tapering-in-patients-with-relapsed-or-refractory-multiple-myeloma-receiving-subcutaneous-daratumumab-part-3-of-the-open-label-multicenter-phase-1b-pavo-study
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Conclusion: Rapid corticosteroid tapering over 3 or 2 weeks is safe in patients with relapsed or refractory multiple myeloma receiving SC daratumumab. These data help guide future SC daratumumab combinations (ie, T-cell redirectors, CAR T-cell, or checkpoint inhibitors), where limiting concurrent corticosteroids may be preferred.
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I just had to think of the remarks from JNJ's Lebowitz a while ago, who said that in that earlier lung trial the concern was that steroids are taking away from the immune response. He adds: we have developped (and into the clinic) a steroid sparing regimen where we can get the streroids off -and we needed the SC to do that
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Are we now back to dara in solid tumours?
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Or are you thinking of Amivantamab?
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to convince JNJ, Genmab would need to start a trial in solid tumors soon, but if you read the press release, leukemia or lymphoma looks more realistic https://ir.genmab.com/news-releases/news-release-details/genmab-signs-agreement-janssen-next-generation-cd38-antibody/
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@Doublo: Det er altid svært at forudsige, hvorfor du altid bør være tro mod din egen personlige investeringsstrategi (kort/mellem/langsigtet investor, evt. nedre smertegrænse kursmæssigt og øvre grænse for gevinsthjemtagning). Hvis du er bekymret om forskydning på den korte bane, så er en potentiel volatil aktie som GEN, ikke nødvendigvis den som du skal være tungt lastet i.
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Novartis (NVS) Q1 2021 Earnings Call Transcript https://www.fool.com/earnings/call-transcripts/2021/04/27/novartis-nvs-q1-2021-earnings-call-transcript/
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Pensionist...Du er slet ikke alene. Jeg tror at de fleste af os her i chatten klart ved at tvisten ligger et vist negativt pres på kursen.
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God morgen.
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Onsdagens aviser med DSV Panalpina, GN og Mærsk https://www.proinvestor.com/investornyt/674496/onsdagens-aviser-med-dsv-panalpina-gn-og-maersk
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Ja ingen tvivl og JNJ sagen er en negativ ting for Genmab. Men det negative er jo indregnet i analytiker targets. Så hvis vi antager targets er 3 mdr gamle og ca. 2500 i snit bør Genmab rykke 300kr indenfor kommende 9 mdr. Der kan så komme positive eller negative triggers undervejs. En afklaring af JNJ tvisten vil helt klart være positivt. Med kurs potential på 300 kr på 9 mdr bør Genmab rykke ca. 30 kr per måned i snit. Hvis kursen ikke rykker og der ikke er negativt nyt bør man overveje at sup
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Biontech ser ud til at have en mulig seriøs mRNA-baseret konkurrent til Kesimpta ift MS. Nyhed tilbage fra Januar https://investors.biontech.de/news-releases/news-release-details/biontech-publishes-data-novel-mrna-vaccine-approach-treat/
Rationaly i think they'll wait for hexacd38 for solids
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