Genmab — April 2021

[StockBull]

Ja det kan der være noget om Vitus / JV

[Helge_LarsenPI-redaktør]

Aktier/tendens: Rekordhumør aftager - fokus ses atter på grønne aktier https://www.proinvestor.com/investornyt/674357/aktier-tendens-rekordhumor-
aftager-fokus-ses-atter-pa-gronne-aktier

[E_L]

Potent preclinical activity of HexaBody-DR5/DR5 in relapsed and/or refractory multiple myeloma https://ashpublications.org/bloodadvances/article/5/8/2165/475774/Potent-preclinical-activity-of-HexaBody-DR5-DR5-in

[Plimsoller]

Gad vide hvor mange penge Biden egentlig tror at han kan få ind ved at indføre højere beskatning af kapitalindkomster over 1 mio. Jeg har ikke selv set det, men det lyder lidt som en crowd pleaser som nogle af de forsleg vi kender herhjemme. Desuden så har befolkningsgruppen med så høje aktieindkomster råd til en god revisor, og det betyder en del i USA.

[Bulder]

Nice E L. So if they can't pursue hexacd38 in MM, they have dr5/dr5 in stead.

[E_L]

very exciting!

[Darvin]

Thanks E L

[GeorgeBest]

Presume they can only use it for patients not on dara anymore? Probably only later lines of treatment?

[E_L]

you mean from a JNJ perspective?

[Darvin]

They write "cytotoxicity can be enhanced via combination with bortezomib, daratumumab, or lenalidomide"

[E_L]

I think they can use other drugs for MM, as long as it isn't
CD38

[GeorgeBest]

Yes okay, makes sence

[E_L]

i think it is funny how they write 'Daratumumab showed additive effects when combined with HexaBody-DR5/DR5' ; as in: the big multiple blockbuster could help a bit, instead of writing DR5 could help Dara a bit lol

[E_L]

but anyway, even more interested to see the first clinical data now in solids, to see if this isn't too toxic in human

[JørgenVarnæs]

GEN said update on DR5 during 2021 - and primary completion in dec21. Do we know anything more specific?

[kkjoel]

Was just about to ask the same
...

[Sukkeralf]

No

[JørgenVarnæs]

Asco er vel for tidligt? Er der en konference i efteråret, der passer?

[Sukkeralf]

ESMO er vel bedste bud - plejer at ligge i september

[Sukkeralf]

Det kan evt også blot være en opdatering hos Genmab selv - specielt hvis data er lidt mudrede