Genmab — Marts 2021

E_L

IV offcourse for now

E_L

and then hope the dose they end up with is small enough to put it through in SC

GeorgeBest

Tak til Helge for at arrangere denne unike mulighed for interaction med JvdW

E_L

so I guess we learned there is a maximum to the time JNJ can think about HexaBody-CD38 , which is they 'can in theory wait for the clinical data from two clinical studies'

E_L

I don't understand why he didn't give us the Dara price hike; he did so the last 2 times? Maybe there was no hike... Has anyone seen it anywhere else?

Helge_LarsenPI-redaktør

Tak GB og tusinde tak til alle for de skarpe spørgsmål. Desværre var der ikke plads til dem alle indenfor tidsrammen.

Solsen

CD37 glæder jeg mig også til...

Bulder

I morgen kommer der SH-tal. Holder du udkig Helge? Gerne for januar også.

Solsen

Masser af potentiale i de stoffer vi kender.

E_L

Dara up to 14% of the frontline patients, last time we heard i think
was 12%?

Helge_LarsenPI-redaktør

Jeps Bulder.

Plimsoller

Glofitamab.

Plimsoller

Gennembrud i kræftbehandling: »På mindre end et døgn svandt tumorerne ind og blev bløde«

B.T. (www.bt.dk)

Solsen

Mærkeligt at jeg ikke kan finde hexa-cd38 på CT. Men på EUs liste https://www.clinicaltrialsregister.eu/ctr-search/trial/2020-003781-40/SE

E_L

the question on Tisotumab Vedotin was not very precise, but i think Jan is referring to peak sales for cervical cancer there; that amount could get much higher if it works in other indications

Solsen

I linket som plimsoller lagde op er endnu et link, hvor bispecifikke i solide omtales positivt. Kunne være Gen1046 https://sundhedspolitisktidsskrift.dk/nyheder/4467-behandlingsrevolution-indenfor-lymfekraeft-vi-har-set-hvordan-tumorerne-pa-mindre-end-et-dogn-svandt-ind-og-blev-helt-blode-det-er-naermest-uvirkeligt.html og bemærk at epco er med i omtalen.

E_L

@Solsen ; it isn't on CT yet, i also searched for it a while ago; I actually wondered if Genmab was hoping they will not have to go through the trouble and JNJ will choose to opt in soon and do it for them...

E_L

and on 16:41 ; it is; Hutchings is working on both Glofi and Epco

E_L

it is taken from the article in the 13:43 link i believe

GeorgeBest

Epco has the lead over glofi on safety and subcu, it might of course change if Roche a subcu version for glofi, but so far there is not clear proof of that.