Genmab — Februar 2021
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Glofitamab is an investigational CD20xCD3 T-cell engaging bispecific antibody designed to target CD20 on the surface of B-cells and CD3 on the surface of T-cells. This dual targeting activates and redirects a patient’s existing T-cells to engage and eliminate target B-cells by releasing cytotoxic proteins into the B-cells. Glofi is based on a novel structural format which we call ‘2:1’, which refers to the structure of the antibody.
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I wonder if Genmab i working on something like this https://www.nature.com/articles/d41586-019-03495-3
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E L - therefore it looks like Roche is planning for Mosunetuzumab for first line and Glofitamab for later lines
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and we know Jan want to put Epcoritamab in first line, and Epcoritamab is much more efficiant than Mosunetuzumab, therefore big advantage for Genmab
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Ingen nyheder med nu +17% i Seagen https://finance.yahoo.com/quote/SGEN?p=SGEN Besynderligt...
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Jeg sidder også og roder efter nyheder. Mon der er noget M&A hurlumhej i beggrunden?
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...potential inclusion in s&p 500
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Lidt anderledes end første gang GEN kom i C20 - dengang var reaktionen lodret ned og ud på røv og albuer...
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God morgen.
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Meg Tirrell
@megtirrellA deep dive into the effect of the Defense Production Act on a rare disease drug, Horizon’s Tepezza, for thyroid eye disease, and the impact it’s had on patients as manufacturing lines were diverted to a #covid19 vaccine https://twitter.com/megtirrell/status/1357851653152641024
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