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Genmab — Januar 2021

Planlagt Fastgjort Låst Flyttet Genmab
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  • E Offline
    E Offline
    E_L
    wrote on sidst redigeret af
    #654

    Dara is fully established, it is not a new drug, most MD’s will already have had experience with it and a lot of them even with SC. You can see from the numerous twitter reactions how enthusiastic most MD’s are. It is the first and only therapy and It will go straight to first line.

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    • E Offline
      E Offline
      E_L
      wrote on sidst redigeret af
      #655

      Besides the 4000 new patients expected to get diagnosed this year, there are many currently waiting for new treatment. In addition, amyloidosis is significantly under-diagnosed; I expect that 4000 number to go up over the next few years when MD’s learn what to look for. JNJ already started an awareness campaign.

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      • G Offline
        G Offline
        GeorgeBest
        wrote on sidst redigeret af
        #656

        You convinced me E L. At least 400M $ this year 😄

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        • BulderB Offline
          BulderB Offline
          Bulder
          wrote on sidst redigeret af
          #657

          Peaksale will be significantly greater than $200mio. This source estimates the total market as $6,7bn in 5 years, and with dara as dominant treatment it will easily reach about 1/5-1/4 of MM sales, which already was 4bn last year. https://www.researchandmarkets.com/reports/4661556/amyloidosis-treatment-market-size-share-and

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          • troldmandenT Offline
            troldmandenT Offline
            troldmanden
            wrote on sidst redigeret af
            #658

            So EL what is your total estimate for dara sales i 2021?

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            • Helge_LarsenPI-redaktørH Offline
              Helge_LarsenPI-redaktørH Offline
              Helge_LarsenPI-redaktør
              wrote on sidst redigeret af
              #659

              E L . I knew you were joking. 🙂 I agree that peak sales can easily get much higher.

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              • BulderB Offline
                BulderB Offline
                Bulder
                wrote on sidst redigeret af
                #660

                Han mangler et nul: 2000 mio $

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                • BulderB Offline
                  BulderB Offline
                  Bulder
                  wrote on sidst redigeret af
                  #661

                  om 5 år

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                  • BulderB Offline
                    BulderB Offline
                    Bulder
                    wrote on sidst redigeret af
                    #662

                    For at summe op: Novod regner med 4bn for tepro i thyroid. 3-3½bn for ofa i RMS. Hvis hertil lægges 2 bn for dara i amy, bliver det tilsammen lige så meget som dara i MM.

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                    • E Offline
                      E Offline
                      E_L
                      wrote on sidst redigeret af
                      #663

                      @troldmanden i have +- $5.5bn for this year

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                      • S Offline
                        S Offline
                        Skyggen
                        wrote on sidst redigeret af
                        #664

                        @ Bulder det giver 9-9,5 mia i andre indikationer end dara det kommer dara vel ikke i nærheden af i år eller hvordan vurdere du det 🙂

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                        • BulderB Offline
                          BulderB Offline
                          Bulder
                          wrote on sidst redigeret af
                          #665

                          nej i 2025. Og royalty for tepro (6%)og ofa (10%) er noget mindre end for dara. Dara vil år nærme sig 6 mia i MM og amy tilsammen.Tror jeg.

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                          • BulderB Offline
                            BulderB Offline
                            Bulder
                            wrote on sidst redigeret af
                            #666

                            Salg - ikke royalty - og $

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                            • BulderB Offline
                              BulderB Offline
                              Bulder
                              wrote on sidst redigeret af
                              #667

                              Er der forresten nogen, der ved om royalty-trappen for dara starter forfra ved 12% i den nye indikation?

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                              • G Offline
                                G Offline
                                GeorgeBest
                                wrote on sidst redigeret af
                                #668

                                Ved det ikke, men vil tro det er en fælles trappe med MM. Ellers havde vi hørt om det...

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                                • SolsenS Offline
                                  SolsenS Offline
                                  Solsen
                                  wrote on sidst redigeret af
                                  #669

                                  Det tror jeg bestem ikke. Men muligt JNJ gør det 😉

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                                  • troldmandenT Offline
                                    troldmandenT Offline
                                    troldmanden
                                    wrote on sidst redigeret af
                                    #670

                                    Rolity starter ikke forfra. Trappen opgøres på totalt salg over et regnskabsår

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                                    • troldmandenT Offline
                                      troldmandenT Offline
                                      troldmanden
                                      wrote on sidst redigeret af
                                      #671

                                      EL sounds about right. Moste of that revenue increase will though be eaten up by the dollar

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                                      • S Offline
                                        S Offline
                                        Skyggen
                                        wrote on sidst redigeret af
                                        #672

                                        @ Bulder mange tak for svar 🙂

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                                        • DarvinD Offline
                                          DarvinD Offline
                                          Darvin
                                          wrote on sidst redigeret af
                                          #673

                                          Nu er priser om lørdagen måske ikke særlig pålidelige, men Tradegate m.fl sætter priser på ca 2.730 - så måske vi mandag klipper snoren på de 2.700 grundigt

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