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Genmab — August 2020

Planlagt Fastgjort Låst Flyttet Genmab
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  • H Offline
    H Offline
    Hamming
    wrote on sidst redigeret af
    #1003

    Lidt cd20/cd3 weekendlæsning https://www.nature.com/articles/s41540-02
    0-00145-7

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    • H Offline
      H Offline
      Hamming
      wrote on sidst redigeret af
      #1004

      https://www.nature.com/articles/s41540-020-00145-7

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      0
      • Helge_LarsenPI-redaktørH Offline
        Helge_LarsenPI-redaktørH Offline
        Helge_LarsenPI-redaktør
        wrote on sidst redigeret af
        #1005

        God morgen. 🙂

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        • T Offline
          T Offline
          transalp
          wrote on sidst redigeret af
          #1006

          Go morgen.. 🙂

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          0
          • E Offline
            E Offline
            E_L
            wrote on sidst redigeret af
            #1007

            Overcoming resistance to rituximab in relapsed non-Hodgkin lymphomas by antibody-polymer drug conjugates actively targeted by anti-CD38 daratumumab https://www.sciencedirect.com/science/article/abs/pii/S0168365920304831

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            • E Offline
              E Offline
              E_L
              wrote on sidst redigeret af
              #1008

              Optimal Approach to the Treatment of Young Adults with Acute Lymphoblastic Leukemia in 2020
              https://www.sciencedirect.com/science/article/pii/S0037196320300275

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              • B Offline
                B Offline
                bibob
                wrote on sidst redigeret af
                #1009

                Ved ikke om dette fra 27 aug. på Clical trials ( DREAMM 7 ) study , har været vist ?? https://www.clinicaltrials.gov/ct2/show/NCT04246047?term=Darzalex&draw=4&rank=128

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                • SolsenS Offline
                  SolsenS Offline
                  Solsen
                  wrote on sidst redigeret af
                  #1010

                  Det er modigt af GSK må man sige. Det forsøg tror jeg de taber på bivirkninger og PFS, men umiddelbar effekt på ORR, CR kan jeg ikke gætte udfaldet. Men vigtigt forsøg for JNJ/Genmab at vinde.

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                  • T Offline
                    T Offline
                    transalp
                    wrote on sidst redigeret af
                    #1011

                    Go morgen.. ny dag.. 🙂

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                    0
                    • Helge_LarsenPI-redaktørH Offline
                      Helge_LarsenPI-redaktørH Offline
                      Helge_LarsenPI-redaktør
                      wrote on sidst redigeret af
                      #1012

                      God morgen. 🙂

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                      0
                      • S Offline
                        S Offline
                        Sukkeralf
                        wrote on sidst redigeret af
                        #1013

                        KOL view Kesimpta

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                        0
                        • S Offline
                          S Offline
                          Sukkeralf
                          wrote on sidst redigeret af
                          #1014

                          Summary points from expert feedback:

                          Uptake of Kesimpta will be brisk as it is a known mechanism and modality
                          Kesimpta’s monthly convenience will drain market share from older injectables
                          No clear difference on safety/efficacy for anti-CD20 mAbs like Kesimpta and Roche’s Ocrevus

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                          • S Offline
                            S Offline
                            Sukkeralf
                            wrote on sidst redigeret af
                            #1015

                            KOL expects 50/50 split on patient preference between Kesimpta’s monthly injection and Ocrevus’ biannual infusion
                            Newly diagnosed patients will favour Kesimpta among the anti-CD20s because of the added control of self-administration

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                            • S Offline
                              S Offline
                              Sukkeralf
                              wrote on sidst redigeret af
                              #1016

                              Just a moment...

                              favicon

                              (www.firstwordpharma.com)

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                              0
                              • Helge_LarsenPI-redaktørH Offline
                                Helge_LarsenPI-redaktørH Offline
                                Helge_LarsenPI-redaktør
                                wrote on sidst redigeret af
                                #1017

                                Tak Sukker. 🙂

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                                0
                                • SolsenS Offline
                                  SolsenS Offline
                                  Solsen
                                  wrote on sidst redigeret af
                                  #1018

                                  Lyder godt Sukker 🙂

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                                  0
                                  • G Offline
                                    G Offline
                                    GeorgeBest
                                    wrote on sidst redigeret af
                                    #1019

                                    Hvis Kesimpta kan dele markedet for nye patienter 50/50 med Ocrevus, så er det bedre end hvad der tidligere er estimeret. Vil være rigtig godt 🙂

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                                    • B Offline
                                      B Offline
                                      bibob
                                      wrote on sidst redigeret af
                                      #1020

                                      God morgen. :-).

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                                      0
                                      • B Offline
                                        B Offline
                                        bibob
                                        wrote on sidst redigeret af
                                        #1021

                                        Bliver spændende at se hvor hurtigt Kesimpta penetrerer markedet.

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                                        • SolsenS Offline
                                          SolsenS Offline
                                          Solsen
                                          wrote on sidst redigeret af
                                          #1022

                                          Novartis har et MS stof på markedet der omsætter for små $3bn og som går af patent. Det forventes at de hurtigt vil skifte over til Kesimpta. Så det kan godt blive med raketfart de lægger fra land 🙂

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