Genmab — August 2020
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Dejlig artikel, tak for den butterboy
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GEN1044 (DuoBody
-CD3x5T4) started recruiting in July https://www.clinicaltrials.gov/ct2/history/NCT04424641?A=1&B=2&C=merged#StudyPageTop -
GEN1046 still steadily adding locations, all recruiting https://www.clinicaltrials.gov/ct2/history/NCT03917381?A=9&B=10&C=merged#StudyPageTop
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Enapotamab almost all recruiting as well https://www.clinicaltrials.gov/ct2/history/NCT02988817?A=16&B=17&C=merged#StudyPageTop
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Mht epcoritamab, så tåler denne genlæsning. “Jeg har aldrig set så potent et lægemiddel til den her type patienter“ og “ lige så effektiv som CART-T og mere sikker” https://haematologisktidsskrift.dk/sygdomme/lymfoma/720-subkutant-bispecifikt-cd3-cd20-antistof-mulig-konkurrent-til-car-t.html
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puha Darvin det er jo NSFW materiale du deler der

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De omtaler ikke den okulare toksicitet https://haematologisktidsskrift.dk/sygdomme/myeloma/739-dansk-optimisme-efter-ema-godkendelse-af-ny-myelomatose-behandling.html
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Immatics Announces European Clinical Expansion of its Adoptive Cell Therapy Programs https://investors.immatics.com/news-releases/news-release-details/immatics-announces-european-clinical-expansion-its-adoptive-cell
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Immatics’ clinical product class ACTengine
is a personalized approach for patients with advanced solid cancers. Patient’s own T cells are genetically modified to express a novel proprietary TCR cognate to one of Immatics’ cancer targets identified by its proprietary XPRESIDENT
target discovery platform. -
No news yet from ADCT "Announced FDA lifted partial clinical hold on pivotal Phase 2 trial of Cami for relapsed or refractory Hodgkin lymphoma: In July 2020, the Company announced that the FDA had lifted the partial clinical hold on its pivotal Phase 2 clinical trial of camidanlumab tesirine (Cami, formerly ADCT-301) in patients with relapsed or refractory Hodgkin lymphoma (HL).
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