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Genmab — Juli 2020

Planlagt Fastgjort Låst Flyttet Genmab
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  • B Offline
    B Offline
    bibob
    wrote on sidst redigeret af
    #965

    God morgen. :-).

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    • B Offline
      B Offline
      bibob
      wrote on sidst redigeret af
      #966

      Tisotumab shows favorable activity in Ovarian cancer. https://www.onclive.com/view/tisotumab-vedotin-shows-favorable-activity-in-recurrent-or-metastatic-cervical-cancer?eKey=amFuYm9ydXAxOTc4QGdtYWlsLmNvbQ==

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      • S Offline
        S Offline
        Sukkeralf
        wrote on sidst redigeret af
        #967

        Cervical cancer

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        • M Offline
          M Offline
          Mogan
          wrote on sidst redigeret af
          #968

          God morgen 😉

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          • Helge_LarsenPI-redaktørH Offline
            Helge_LarsenPI-redaktørH Offline
            Helge_LarsenPI-redaktør
            wrote on sidst redigeret af
            #969

            Tak bibob.

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            • B Offline
              B Offline
              bibob
              wrote on sidst redigeret af
              #970

              Tak Sukker. Selvfølgelig. 😉

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              • E Offline
                E Offline
                E_L
                wrote on sidst redigeret af
                #971

                Phase 3 Amivantamab trial,
                1000 participants!!

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                • E Offline
                  E Offline
                  E_L
                  wrote on sidst redigeret af
                  #972

                  A Study of Amivantamab and Lazertinib Combination Therapy Versus Osimertinib in Locally Advanced or Metastatic Non-Small Cell Lung Cancer (MARIPOSA) https://www.clinicaltrials.gov/ct2/show/NCT04487080?recrs=ab&cond=Lung+Cancer&sfpd_s=07%2F14%2F2020&sfpd_d=14&sel_rss=new14

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                  • M Offline
                    M Offline
                    Mcjean
                    wrote on sidst redigeret af
                    #973

                    Wouw thats a lot, isnt it?

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                    • SolsenS Offline
                      SolsenS Offline
                      Solsen
                      wrote on sidst redigeret af
                      #974

                      Yes it is. They perhaps need power to show better effect. What do Osimertinib have in revenue ?

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                      • SolsenS Offline
                        SolsenS Offline
                        Solsen
                        wrote on sidst redigeret af
                        #975

                        Tagrisso: $982M (+56%) Q120

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                        • E Offline
                          E Offline
                          E_L
                          wrote on sidst redigeret af
                          #976

                          Novartis also with a new trial , for patients that want to switch to Ofa from another CD20 https://www.clinicaltrials.gov/ct2/show/NCT04486716?term=NCT04486716&draw=2&rank=1

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                          • SolsenS Offline
                            SolsenS Offline
                            Solsen
                            wrote on sidst redigeret af
                            #977

                            Lidt mere om Lazertinib https://www.fiercebiotech.com/biotech/janssen-taps-south-korea-s-yuhan-for-tagrisso-rival Gode data og baren er sat højt.

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                            • SolsenS Offline
                              SolsenS Offline
                              Solsen
                              wrote on sidst redigeret af
                              #978

                              Barren skulle der stå 😉

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                              • J Offline
                                J Offline
                                Joakim_Von_And
                                wrote on sidst redigeret af
                                #979

                                De stoffer I nævner Amivantamab, Lazertinib..Hvem har de forbindelse til ? Kan ikke finde ud af om det er godt eller skidt for genmab.

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                                • G Offline
                                  G Offline
                                  gentogen
                                  wrote on sidst redigeret af
                                  #980

                                  Amivantamab (JNJ-61186372) is a bispecific antibody that targets EGFR and cMet, two validated cancer targets. The two antibodies used to create amivantamab (JNJ-61186372) were both created by Genmab.

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                                  • Helge_LarsenPI-redaktørH Offline
                                    Helge_LarsenPI-redaktørH Offline
                                    Helge_LarsenPI-redaktør
                                    wrote on sidst redigeret af
                                    #981

                                    God morgen. 🙂

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                                    • B Offline
                                      B Offline
                                      bibob
                                      wrote on sidst redigeret af
                                      #982

                                      God morgen. 🙂

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                                      0
                                      • S Offline
                                        S Offline
                                        Sukkeralf
                                        wrote on sidst redigeret af
                                        #983

                                        Der må falde en milestone når fase III med amivantamab starter op - ligeledes når første registreringsansøgning indsendes sidt på året. Bliver spændende at se hvor backloaded disse aftaler er

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                                        • S Offline
                                          S Offline
                                          Sukkeralf
                                          wrote on sidst redigeret af
                                          #984

                                          Nogen der husker strukturen på en lignende aftale. Den er selvfølgelig backloaded i høj grad, men må også være ret simpel, da man jo for mange af programmerne ikke kendte targets og dermed mulige indikationer. Så mon den alene går på første indikation der kommer hele vejen, for de milestones det gælder klinisk udvikling og registrering. Gætter på at mindst halvdelen af milestonepakken er salgsmilestones

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