Genmab — Juni 2020
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TV kombinationstudiet i cervical cancer har estimated primary completion date i april 2021https://clinicaltrials.gov/ct2/show/NCT03786081?cond=tisotumab+vedotin&draw=2&rank=8
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Iovance LN-145 viste ORR på 44% ved ASCO 2019 på 27 pre-treated, recurrent cervical cancer patienter. Bliver nok en hård konkurrent til TV, men er jo nok et års tid bagefter tidsmæssigt https://www.evaluate.com/vantage/articles/news/snippets/asco-2019-iovance-enjoys-pre-asco-bounce
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Bryan Garnier hæver fair value til 2150 fra 2000. Fortsat Neutral
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BG: A 24% ORR puts it at the forefront of the cervical space
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BG: TV seems to have an edge over Keytruda in 2L+ setting
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BG: This success paves the way for 1L use
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BG: TV’s reach could go way beyond cervical cancer
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BG: Genmab on track to become an integrated biopharma company
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BG: We lift our FV from DKK2,000 to DKK2,150 following the review of our
scenario on TV as well as our updated risk-free rate (0.6% vs 1.6%) and risk premium -
thanks @Stockwatch1
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The TIL therapy under investigation in this clinical trial (LN-145) is derived through isolation of a patient’s own naturally occurring TIL from a sample of cancerous tumor removed from the patient. After TIL are extracted from the tumor, they are multiplied in a laboratory until billions of TIL are obtained. https://www.iovance.com/clinical/c-145-04-cervical-carcinoma/
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Yes sounds similar to CAR-T
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ah that link doesn't work like that ,
try https://www.evaluate.com/vantage/articles/events/upcoming-events/upcoming-events-genmabs-route-market-and-late-stage-data -
ifølge bussiness wire vil markedet for livmoderhalskræft ramme i nærheden af 17,9 milliarder dollar i 2022, hvis vi antager at Tiso kommer i første eller 2. linje er der nogen der har et forsigtigt bud på hvor mange procent af den kage man vil kunne få anddel i
? https://www.businesswire.com/news/home/20191211005568/en/Global-Cervical-Cancer-Drugs-Market-Report-2020 -
en helt anden ting, hold op hvor er det dejligt, at der kommer nye behandlinger indenfor dette område, skrækkelig sygdom med katastrofale konsekvenser for alt for mange unge kvinder
) that is a difficult treatment though LN 145, isn't it a bit like Car-T?
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