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Genmab — Maj 2020

Planlagt Fastgjort Låst Flyttet Genmab
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  • G Offline
    G Offline
    GeorgeBest
    wrote on sidst redigeret af
    #1456

    Halozyme Earns $15M Milestone Payment From Janssen https://www.socaltech.com/halozyme_earns___m_milestone_payment_from_janssen/s-0079866.html

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    • T Offline
      T Offline
      transalp
      wrote on sidst redigeret af
      #1457

      Go morgen.. 🙂

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      • B Offline
        B Offline
        bibob
        wrote on sidst redigeret af
        #1458

        God morgen. 🙂

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        • T Offline
          T Offline
          transalp
          wrote on sidst redigeret af
          #1459

          Det er jo gode ord om amivantamab, GB deler
          , hvor langt er det, i processen? Har ikk ordentlig styr på det..

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          • B Offline
            B Offline
            bibob
            wrote on sidst redigeret af
            #1460

            Teclistamab. https://www.fiercebiotech.com/biotech/j-j-links-bcma-bispecific-to-67-response-rate-myeloma?mkt_tok=eyJpIjoiTURRek5HRTRaVEEyWWpKbCIsInQiOiJVQUpLVjB3SXZFRnM5TXBpNVpoa2pabE14Mitzd1hZQVRYM1MrQ2ZOcVd2M1BraGJFaVpJdkt0d1AxclZaeXFLMU1qalpMQ1d1bTE5c2h5ZmNqU3RUa0NZaE5vVnlQZXFwRG5Tak5rQ2tBUjBKYjlBOG1LQXFUVmhQSEZhcWhMUFwvOUdVc0xoVVlkSUxGcDRlRGRsVVpRPT0ifQ%3D%3D&mrkid=41140432

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            • G Offline
              G Offline
              GeorgeBest
              wrote on sidst redigeret af
              #1461

              Transalp - Janssen forventer at indsende en ansøgning til godkendelse sidst på året. Hvilket JNJ sagde i forbindelse med Q2 regnskab.

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              • G Offline
                G Offline
                GeorgeBest
                wrote on sidst redigeret af
                #1462

                Q1 regnskab

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                • J Offline
                  J Offline
                  JKY_VH
                  wrote on sidst redigeret af
                  #1463

                  God morgen;-)

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                  • Helge_LarsenPI-redaktørH Offline
                    Helge_LarsenPI-redaktørH Offline
                    Helge_LarsenPI-redaktør
                    wrote on sidst redigeret af
                    #1464

                    God morgen. 🙂

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                    • T Offline
                      T Offline
                      transalp
                      wrote on sidst redigeret af
                      #1465

                      Tak GB ..????

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                      • T Offline
                        T Offline
                        transalp
                        wrote on sidst redigeret af
                        #1466

                        Beklager ???? Prøvde en smily ..:)

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                        • BulderB Offline
                          BulderB Offline
                          Bulder
                          wrote on sidst redigeret af
                          #1467

                          Tak GB. Så fik vi tal på amivantamabs potentiale. 100.000 koreanere havde NSCLC sidste år. Heraf havde 50% EGFR mutationer. Og heraf havde 10% EGFR Exon20ins mutationer. På verdensplan bliver det til en del.

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                          • S Offline
                            S Offline
                            Sukkeralf
                            wrote on sidst redigeret af
                            #1468

                            Bulder fra Janssens BTD meddelelse står der:

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                            • S Offline
                              S Offline
                              Sukkeralf
                              wrote on sidst redigeret af
                              #1469

                              About Non-Small Cell Lung Cancer (NSCLC)
                              In the U.S., lung cancer is the second most common cancer in both men and women, after skin cancer; NSCLC makes up 80-85 percent of all lung cancers.[8],[9] The main subtypes of NSCLC are adenoca rcinoma, squamous cell carcinoma, and large cell carcinoma.10 The most common driver mutation for NSCLC is the EGFR genetic alteration, which is a receptor tyrosine kinase that helps cells grow and divide.[10]

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                              • S Offline
                                S Offline
                                Sukkeralf
                                wrote on sidst redigeret af
                                #1470

                                EGFR mutations are present in 10 to 15 percent of patients with NSCLC and occur in 40 to 50 percent of Asian patients who have NSCLC adenocarcinoma.[11],[12],[13] EGFR exon 20 insertion mutations identify a distinct subset of lung adenocarcinomas, accounting for at least nine percent of all EGFR mutations.[14] The five-year survival rate for patients with metastatic NSCLC is currently six percent.[15]

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                                • S Offline
                                  S Offline
                                  Sukkeralf
                                  wrote on sidst redigeret af
                                  #1471

                                  Site Maintenance

                                  favicon

                                  (www.jnj.com)

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                                  • S Offline
                                    S Offline
                                    Sukkeralf
                                    wrote on sidst redigeret af
                                    #1472

                                    Så god grund til at man har kørt studiet i Sydkorea

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                                    • BulderB Offline
                                      BulderB Offline
                                      Bulder
                                      wrote on sidst redigeret af
                                      #1473

                                      Ja, det er så mere udbredt derovre. Men på verdensplan er det også mange. 10-15% af al NSCLC har EGFR mutationer. Heraf igen 10 % med Exon 20.

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                                      • Helge_LarsenPI-redaktørH Offline
                                        Helge_LarsenPI-redaktørH Offline
                                        Helge_LarsenPI-redaktør
                                        wrote on sidst redigeret af
                                        #1474

                                        Amivantamab og forsøget i Korea har vist kørt under radaren. Mener dog, at vi har haft det oppe i en Q&A på et tidspunkt.

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                                        • S Offline
                                          S Offline
                                          Sukkeralf
                                          wrote on sidst redigeret af
                                          #1475

                                          Det synes jeg nu ikke Helge, men det er nok kommet som en overraskelse for de fleste, at de fik BTD i marts og regne med at indsende registeringsansøgning i slutningen af året. Det er målrettet !

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