Genmab — Maj 2020

[Bulder]

yes and the combo opportunities with small molecules and epco

[Sukkeralf]

Such a strong engine they have - again most BP must look at that and be envious

[kkjoel]

and hungry maybe...

[kkjoel]

Åh nej, det hedder: super hungry

[E_L]

@Bulder it seems he already knows what the next epco
trial will look like...

[Solsen]

Its a good option on cami-t. I think the antibody conjugate are much better than SGENs Adcetris, which sold for $164 mln in Q120 in north america. BUT safety could be an issue.

[Sukkeralf]

there have been a lot of focus on next generation BTK inhibitors - if ot not with ibrutinib then maybe one of those

[Solsen]

JW was clever not to disclose which small molecule he preferred

[Solsen]

Yes sukker its crowded.

[Sukkeralf]

The warheads on ADCT´s ADCs are much more potent but as you say safety is the big issue. Ohad Hammer did not like ADCTs their approch

[Solsen]

Thats the reason Iam not sure about the future. But again here Genmab was wise not to put more money in something that could be too toxic.

[E_L]

i am curious now on "Genmab's next generation AB technologies for making better COVID-19 antibody therapeutics.."

[E_L]

i don't want to read too much into it, but curious

[Solsen]

Very interesting that Genmab are involved. But I think its all over before they are able to have anything ready.

[nohope]

I sure don´t hope it is Genmab with AB who is going to save us from

[nohope]

Covid-19

[nohope]

Would be great if they could pick something as a generalist against vira for the future pandemics - but Covid-19 should be gone long time before.

[nohope]

Something that could control the cytokinstorm.

[kkjoel]

Sidder her med tilbageholdt åndedræt.. det man har venter på i nogle år sker for øjnene af en. En art
déjà vu

[Solsen]

Mon vi kan lukke i 1900. Så er der kun en dag til 2000 ;-). Hvis vi kan holde tempoet ,,,