Genmab — April 2020
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For all the excitement it generated, the STAT report was little more than a leaked conversation between doctors. It revolved around a trial at the University of Chicago with 125 patients, mostly severely ill with covid-19. One of the doctors is reported as saying that most of the patients had been discharged and only two had died. But even if this is correct, the lack of a placebo group makes it hard to assess the real worth of the drug. The University of Chicago itself warned that drawing any
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Even if the drug proves successful, it is still experimental, and only limited quantities of such drugs are usually available. Gilead has increased production to meet demand for use in trials. On April 5th, it said it had enough to supply more than 140,000 patients.
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These sorts of numbers are larger than would be required by clinical trials, so suggest that Gilead is ramping up production for clinical use. The firm also said it was hoping to increase output again as raw materials became available. Looking further ahead, at even broader use, the firm has set an “ambitious goal” of producing more than 500,000 treatment courses by October, and 1m by the end of the year, from a geographically diverse group of suppliers.
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Genmab tilbage i kanalen https://nbg1.your-objectstorage.com/proinvestor-dev/forum/boards/83827_April_18_genmab.JPG
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Link til Twitter, virker hos mig.
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Amyloidosis: Safety Run-in trial of Phase 3 Dara-CYBORDE trial showed 82% >VGPR with high renal organ response rate https://twitter.com/slentzsch/status/1251703290598916099?s=21
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https://www.clinical-lymphoma-myeloma-leukemia.com/article/S2152-2650(20)30143-9/fulltext
Evolving role of Daratumumab: From backbencher to a frontline agent https://sci-hub.tw/https://www.clinical-lymphoma-myeloma-leukemia.com/article/S2152-2650(20)30143-9/fulltext -
US FDA and EMA accept applications for Roche’s OCREVUS (ocrelizumab) shorter 2-hour infusion time https://www.finanzen.ch/nachrichten/aktien/us-fda-and-ema-accept-applications-for-roches-ocrevus-ocrelizumab-shorter-2-hour-infusion-time-1029105760
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Novartis starting a new "An Open-label Study Evaluating Ofatumumab Treatment Effectiveness and PROs in Subjects With RMS Transitioning From Dimethyl Fumarate or Fingolimod to Ofatumumab (ARTIOS)" https://www.clinicaltrials.gov/ct2/show/NCT04353492?cond=Multiple+Sclerosis&sfpd_s=04%2F06%2F2020&sfpd_d=14&sel_rss=new14
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