Genmab — Februar 2020

[E_L]

10/1 10:38

af E L And I am really not so sure yet what they will guide. For now i think 'over $4bn' ?

[E_L]

i think i stick to that for now, even though you all seem a lot more optimistic

[E_L]

CD38 in Neurodegeneration and Neuroinflammation https://www.mdpi.com/2073-4409/9/2/471

[E_L]

you can click on download pdf for full article

[JKY_VH]

Mit bidrag til bibobs skydetelt er at de guider over $4bn. Jeg er konservativ g beskeden lige som Jan:-)

[Legolas23]

Spændende med luk. 4-5 point op kunne se flot ud.

[Solsen]

Jeg synes at Genmab virker overraskende stærk. Sammenholdt med Helges oplysninger omkring hvor travlt de har i Genmab så tror jeg der er et eller andet under opsejling. Partnerdeal ?

[Legolas23]

Timingen ville være den rette, hvis den kom i morgen.

[bibob]

For min skyld må den gerne komme i dag. ;-). Så bliver det nok ikke guidingen der tar fokus i morgen.

[Solsen]

“CD38 in Neurodegeneration” and link from EL is very interesting. Imagine dara as the drug in Alzheimer, Parkinson etc

[Solsen]

The immunosuppressive effect of anti-CD38 antibodies like daratumumab on plasma cells and plasmablasts could be useful against autoimmune neurological disorders like multiple sclerosis

[Solsen]

CD38 nevertheless represents a very promising target to fight neurodegeneration as well as neuroinflammation due to its close link with aging and experimental evidences from CD38 KO mice.

[Solsen]

Blot et par citater fra artiklen -:)

[Solsen]

Hvis JNJ tror på det og Alzheimers for
søget viser resultater er Genmab doomed.

[Solsen]

https://clinicaltrials.gov/ct2/show/NCT04070378?term=Daratumumab&cond=Alzheimer+Disease&draw=2&rank=1 link til Alzheimers forsøget.

[bibob]

Genmab har jo vist også noget kørende med Lundbeck. ! Det hører vi ikke rigtigt om. Det kan vel i princippet også være cd38. ? ( ikke Dara ).

[E_L]

Lundbeck still has it in their pipeline, on top of my head i think they showed
2025 filing...

[E_L]

i don't think it is cd38

[JKY_VH]

Du mener vel take-over Solsen 19.56?

[bibob]

Ok E L. Still far away. But ongoing.