Genmab — December 2019
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https://www.curevac.com/about-curevac Link til CureVac og interessant læsning
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we were just recently hinting at more trials in this field - New small trial: Desensitization in Kidney Allograft Using Daratumumab (DARDAR) https://clinicaltrials.gov/ct2/show/NCT04204980?term=daratumumab+OR+ofatumumab+OR+tisotumab+OR+Genmab+OR+arzerra+OR+duobody&lupd_s=12%2F18%2F2019&draw=2&rank=2
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1 more : Reduce Intensity Conditioning Donor Stem Cell Transplant for the Treatment of Relapsed Multiple Myeloma - https://clinicaltrials.gov/ct2/show/NCT04205240?term=daratumumab+OR+ofatumumab+OR+tisotumab+OR+Genmab+OR+arzerra+OR+duobody&lupd_s=12%2F18%2F2019&draw=2&rank=5
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GEN1042 with BioNtech started recruiting https://clinicaltrials.gov/ct2/history/NCT04083599?A=1&B=2&C=merged#StudyPageTop
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CureVac's mRNA platform lyder da ret spændende. Det ser ud til, at de kan bygge mRNA sequences i stabil form. Det burde så både kunne bruges til aktivere immunforsvaret "naturligt" mod cancer celler, få cancercellerne til at udstille flere targets (f.eks. mere CD38) eller at tagge cancer celler med et target, der ikke findes andre steder i kroppen, så bivirkninger mindskes.
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probably a fair statement , also given this earlier comment - “The achievement of starting a Phase I/IIa clinical trial with a product candidate developed in only four years is a validation of our highly productive partnership with Genmab,” said Prof. Ugur Sahin, CEO of BioNTech - RE timing
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