Genmab — December 2019

[Bulder]

Let's see if the man himself (Rajkumar) will comment on this

[Bulder]

It doesn't matter much if Belamaf is going to play a role in relapsed setting. I don't think it will have a chance in frontline (possibly deaths).

[Bulder]

Very modest conclusion: Single-agent belantamab mafodotin shows anti-myeloma activity with a manageable safety profile in patients with relapsed or refractory multiple myeloma.

[Bulder]

The Lancet: Two deaths were potentially treatment related

[E_L]

you are probably correct. should we draw any assumptions from this for JNJ-957? I wonder when we will hear anything from that anyway, primary completion is may 2020, maybe ASCO?

[Bulder]

Sorry 8:53, I meant Lonial

[Bulder]

Would be nice with Sukkeralf in on this

[Solsen]

GSK with only 3% cr and 27% grade 3/4. JW nailed it with his prediction about “blue vision”

[peter12]

Nå det var den med 51%
"blurred vision" ?

[Solsen]

nå det var sådan det staves

[peter12]

Tror det...;-)

[E_L]

European Investment Bank provides funding of €50 million to BioNTech as part of the Investment Plan for Europe https://www.globenewswire.com/fr/news-release/2019/12/17/1961450/0/en/European-Investment-Bank-provides-funding-of-50-million-to-BioNTech-as-part-of-the-Investment-Plan-for-Europe.html they can put it straight into the duobodies

[peter12]

Its up 6% in pre-market but lets see

[Bulder]

Det er vel ved at være på tide, at vi hører om filing af ofa i RMS?

[E_L]

they still have 2 weeks lol, swiss precision

[bibob]

E L. I have a swiss watch too. But It's a stop watch. Do you think that's a problem.

[E_L]

[E_L]

What advice can you offer to community hematologists and oncologists treating patients with transplant-ineligible NDMM?

Dr. Mateos: Always try to use the best combination first because the best combinations will benefit almost 100% of newly diagnosed myeloma patients. The maximum benefit is obtained from the first line of therapy, and some transplant-ineligible patients with NDMM will receive only one line of therapy. https://i3health.us/news/adding-daratumumab-to-vmp-for-transplant-ineligible

[E_L]

Genmab article on p 16 http://digitaledition.qwinc.com/publication/?m=53489&l=1&view=issuelistBrowser#{"issue_id":"641494","page":16}

[E_L]

Glaxo’s myeloma Dreamm turns into a nightmare https://www.evaluate.com/vantage/articles/news/trial-results/glaxos-myeloma-dreamm-turns-nightmare