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Genmab — December 2019

Planlagt Fastgjort Låst Flyttet Genmab
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  • E Offline
    E Offline
    E_L
    wrote on sidst redigeret af
    #539

    I am a bit surprised they don't mention hex-cd38...?

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    • E Offline
      E Offline
      E_L
      wrote on sidst redigeret af
      #540

      from Q&A - Jan Van de Winkel We will present a very impressive preclnical data set at the ASH conference in early
      December showing that HexaBody CD38 can effectively kill tumors that are not
      sensitive to Daratumumab...
      Jan Van de Winkel A number of tumors will be presented in Orlando and we certainly think that HexaBody
      CD38 could well provide an option for treatment of solid cancers.

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      • S Offline
        S Offline
        Sukkeralf
        wrote on sidst redigeret af
        #541

        Ja man er ikke helt oppe og ringe - nogen der ved om lever tox problemerne i DR5/DR5 programmet kan være relateret dertil ?

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        • SolsenS Offline
          SolsenS Offline
          Solsen
          wrote on sidst redigeret af
          #542

          Dont you think we get an update on the pipeline in generel.

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          • S Offline
            S Offline
            Sukkeralf
            wrote on sidst redigeret af
            #543

            We will: Genmab speakers will also discuss the company’s pipeline, progress and key goals for 2020

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            • S Offline
              S Offline
              Sukkeralf
              wrote on sidst redigeret af
              #544

              for sure hexaCD38 will be mentioned

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              • S Offline
                S Offline
                Sukkeralf
                wrote on sidst redigeret af
                #545

                its a clinical candidate next year

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                • SolsenS Offline
                  SolsenS Offline
                  Solsen
                  wrote on sidst redigeret af
                  #546

                  I think we have to look at DR5 as a lottery ticket.

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                  • S Offline
                    S Offline
                    Sukkeralf
                    wrote on sidst redigeret af
                    #547

                    Yes but hopefully its the target thats still a problem even with a more potent compound - and not the technology

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                    • E Offline
                      E Offline
                      E_L
                      wrote on sidst redigeret af
                      #548

                      not sure if this video was posted already - ASH 2019 | Early prevention of myeloma: dara for high-risk MGUS and low-risk SMM - https://www.vjhemonc.com/video/quccqyli-m0-early-prevention-of-myeloma-dara-for-high-risk-mgus-and-low-risk-smm/

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                      • E Offline
                        E Offline
                        E_L
                        wrote on sidst redigeret af
                        #549

                        ok, as I was hoping, on CHMP agenda this week Dara SC and for the 2nd time (daratumumab) in combination with bortezomib, thalidomide and dexamethasone https://www.ema.europa.eu/en/documents/agenda/agenda-chmp-agenda-9-12-december-2019-meeting_en.pdf

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                        • G Offline
                          G Offline
                          GeorgeBest
                          wrote on sidst redigeret af
                          #550

                          Bluebird startede 5% op, men er nu minus 1%, så der er da ikke meget CAR-T eufori i aktiekurserne....

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                          • G Offline
                            G Offline
                            GeorgeBest
                            wrote on sidst redigeret af
                            #551

                            TAK-079: Takeda får heller ikke noget boost....

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                            • nohopeN Offline
                              nohopeN Offline
                              nohope
                              wrote on sidst redigeret af
                              #552

                              U-TAK - er verdens løn...

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                              • E Offline
                                E Offline
                                E_L
                                wrote on sidst redigeret af
                                #553

                                the HexaBody-CD38 poster, courtesy Kempen https://twitter.com/KempenLS/status/1204059369480036354

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                                • M Offline
                                  M Offline
                                  mobbyduck1
                                  wrote on sidst redigeret af
                                  #554

                                  nice one EL

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                                  • Helge_LarsenPI-redaktørH Offline
                                    Helge_LarsenPI-redaktørH Offline
                                    Helge_LarsenPI-redaktør
                                    wrote on sidst redigeret af
                                    #555

                                    Sorry..Jeg kan simpelthen ikke læse posteren her på mobilen. Hvad er headlines?

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                                    • BulderB Offline
                                      BulderB Offline
                                      Bulder
                                      wrote on sidst redigeret af
                                      #556

                                      enhanzed cdc compared to dara

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                                      • BulderB Offline
                                        BulderB Offline
                                        Bulder
                                        wrote on sidst redigeret af
                                        #557

                                        did not induce lysis of normal cells but did lisys on NK cells

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                                        • BulderB Offline
                                          BulderB Offline
                                          Bulder
                                          wrote on sidst redigeret af
                                          #558

                                          ellers er det vist det samme som der står i abstr.

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