Genmab — December 2019
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interestingly, InnovaTV 205 adds another arm, TV monotherapy. Adds 30 patients https://clinicaltrials.gov/ct2/history/NCT03786081?A=6&B=7&C=merged#StudyPageTop
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Det gjorde det. Mange aktier og indeks havde det samme løft på det tidspunkt.
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Multiple Myeloma Hub
@MM_Hub
Tomorrow is the official start of #ASH19! We want to know what content you are most looking forward to seeing from the @MM_Hub
during the meeting
https://twitter.com/MM_Hub/status/1202993896248225792 -
Vincent Rajkumar
@VincentRK
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1 t
Ofatumumab maintenance in relapsed chronic lymphocytic leukemia: final analysis of the PROLONG study | Blood Cancer Journal #BCJhttps://www.nature.com/articles/s41408-019-0260-2 -
God morgen.
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Janssen Announces BCMA CAR-T Therapy JNJ-4528 Granted U.S. FDA Breakthrough Therapy Designation for the Treatment of Relapsed or Refractory Multiple Myeloma https://www.prnewswire.com/news-releases/janssen-announces-bcma-car-t-therapy-jnj-4528-granted-us-fda-breakthrough-therapy-designation-for-the-treatment-of-relapsed-or-refractory-multiple-myeloma-300970825.html
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I know I'm a #latebreaker but here are my top 10 abstracts for #ASH19 (no particular order). I tried to focus on things that might affect my practice in the next 2 years. @SandyWong https://twitter.com/ninashah33/status/1203057982948495360
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4 Questions for a Scientist Working on a Revolutionary CAR-T Therapy for Multiple Myeloma https://www.jnj.com/innovation/a-q-a-with-a-scientist-working-on-unique-car-t-therapy-for-multiple-myeloma
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MAIA study: second interim analysis results:https://multiplemyelomahub.com/medical-information/maia-study-second-interim-analysis-results
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Conclusion6
Patients with NDMM who are ineligible for ASCT had a 44% reduced risk of PD or death when treated with dara-Rd compared to Rd alone. Patients receiving dara-Rd had a longer PFS, higher response rate, increased the depth of response and longer duration of response compared to Rd.
Notably, in this trial, 99% of patients were aged 65 or older, and the PFS benefit was maintained regardless of age. The HR for PD or death in patients aged over 75 treated with dara-Rd was 0.63 reflecting
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Det er meget gode data, men ikke overraskende.
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