Genmab — November 2019
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Konkurrent data til EnaV (bencemtinib + pembro) i NSCLS
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God morgen.
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GM. draft ASH Top 10 ( 859, 860, 862, 925 are Dara ) https://twitter.com/mtmdphd/status/1193260261160951808 https://www.myeloma.org/cure-blog/ash-top-10-2019-immune-therapies-again-dominate-news
https://twitter.com/szusmani/status/1192582644170665984 -
Dara + ATRA disappointing: Overall, this approach resulted in a modest prolongation of PFS. Patients with primary DARA-refractory disease did not benefit from the addition of ATRA. However, in patients with ≥PR on DARA monotherapy prior to progression, addition of ATRA and re-intensification of DARA was of marked clinical benefit with an additional 7.8 months of disease control. https://ash.confex.com/ash/2019/webprogram/Paper123383.html
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Men deres patent har ikke så lang levetid mere.
https://www.biopharmadive.com/news/celgene-revlimid-patent-challenge-dr-reddys-ptab/548172/ -
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God morgen.
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Merck and Pfizer's PD-L1 Bavencia ( avelumab ) fejler et PH III forsøg i gastric cancer. https://m.firstwordpharma.com/merck-kgaa-pfizer-say-late-stage-study-bavencio-gastric-cancer-misses-primary-endpoints
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