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Genmab — November 2019

Planlagt Fastgjort Låst Flyttet Genmab
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Denne tråd er blevet slettet. Kun brugere med emne behandlings privilegier kan se den.
  • E Offline
    E Offline
    E_L
    wrote on sidst redigeret af
    #30

    We have another one coming along behind that that uses yet another immune mechanism. What we know so far about mechanisms of resistance to the standard of care CD38 antibodies, is that the levels of CD38 on the myeloma cell are reduced.

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    • E Offline
      E Offline
      E_L
      wrote on sidst redigeret af
      #31

      But CD38 still remains on the myeloma cell, however at lower levels. So the target is still relevant. And we feel there's sufficient retained expression for most patients that we can still go at that target but with these enhanced antibodies. So there would really be an attempt to rescue patients who failed a frontline standard care agent.

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      • S Offline
        S Offline
        Sukkeralf
        wrote on sidst redigeret af
        #32

        Genmab then nedds to speed up HexaBody CD38 so that they are not that far behind Sanofi

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        • B Offline
          B Offline
          bibob
          wrote on sidst redigeret af
          #33

          I'am sure they work hard with that.

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          • Helge_LarsenPI-redaktørH Offline
            Helge_LarsenPI-redaktørH Offline
            Helge_LarsenPI-redaktør
            wrote on sidst redigeret af
            #34

            Ses vi? https://www.proinvestor.com/debat/78610

            1 Reply Last reply
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            • BulderB Offline
              BulderB Offline
              Bulder
              wrote on sidst redigeret af
              #35

              They have the money for it, so it shouldn't be a problem to speed it up a bit. And thx again E L.

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              • E Offline
                E Offline
                E_L
                wrote on sidst redigeret af
                #36

                a small new trial using BMS-986253 / HuMax-IL8 for NSCLC https://clinicaltrials.gov/ct2/show/NCT04123379

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                • B Offline
                  B Offline
                  Bella1
                  wrote on sidst redigeret af
                  #37

                  Børsen nede 11.06?

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                  • B Offline
                    B Offline
                    Bella1
                    wrote on sidst redigeret af
                    #38

                    Fondsbørsen, forstås...

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                    • BulderB Offline
                      BulderB Offline
                      Bulder
                      wrote on sidst redigeret af
                      #39

                      følg med i chat nyheder

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                      0
                      • SolsenS Offline
                        SolsenS Offline
                        Solsen
                        wrote on sidst redigeret af
                        #40

                        Hvis ikke de åbner når vi ikke ATH og festen i dag...

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                        0
                        • B Offline
                          B Offline
                          bikube
                          wrote on sidst redigeret af
                          #41

                          Børsen åbner igen kl. 13.

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                          • E Offline
                            E Offline
                            E_L
                            wrote on sidst redigeret af
                            #42

                            a saw from this message from a Belgian University hospital that one of the area's BMS-986253 is used is Dermatological tumors/ melanoma https://www.uzgent.be/nl/zorgaanbod/mdspecialismen/Geneesmiddelenonderzoek/Lopende-studies/Paginas/Indicatoren-dermatologische-tumoren.aspx (clinicaltrials only mentioned 'advanced cancers' https://www.clinicaltrials.gov/ct2/show/study/NCT03400332?term=BMS-986253&show_locs=Y#locn )

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                            • P Offline
                              P Offline
                              Plimsoller
                              wrote on sidst redigeret af
                              #43

                              Så er de vist oppe igen. Kursen hoppede lige.

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                              0
                              • BulderB Offline
                                BulderB Offline
                                Bulder
                                wrote on sidst redigeret af
                                #44

                                allerede nyt børsstop

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                                • P Offline
                                  P Offline
                                  Plimsoller
                                  wrote on sidst redigeret af
                                  #45

                                  Har de fået deres system fra den samme leverandør som Skat?

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                                  0
                                  • BulderB Offline
                                    BulderB Offline
                                    Bulder
                                    wrote on sidst redigeret af
                                    #46

                                    yes, ansaldobreda

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                                    0
                                    • P Offline
                                      P Offline
                                      Plimsoller
                                      wrote on sidst redigeret af
                                      #47

                                      Pefekt. Så kan de lige smide IC4 togene med ind i erstatningskravet. Rart at have det hele samlet et sted 🙂

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                                      • BulderB Offline
                                        BulderB Offline
                                        Bulder
                                        wrote on sidst redigeret af
                                        #48

                                        Da computerne ikke virker skal de bruge IC4 til at køre rundt i landet og lave nye ejendomsvurderinger.

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                                        • BulderB Offline
                                          BulderB Offline
                                          Bulder
                                          wrote on sidst redigeret af
                                          #49

                                          Jeg tror de inde på Nasdaq fik åbnet fredagsbaren lidt for tidligt.

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                                          0

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