Genmab — Oktober 2019

[E_L]

@Bulder will like this discussion - Subcutaneous Versus IV - https://www.ajmc.com/peer-exchange/review-of-treatment-for-multiple-myeloma/reimbursement-of-subcutaneous-versus-iv-dosing-in-multiple-myeloma

[E_L]

and i guess this is the article the Dutch financial newspaper really interviewed Jan for (in dutch again) https://fd.nl/ondernemen/1318527/terug-aan-de-top-na-tegenvaller-met-kankermedicijn?utm_medium=social&utm_source=twitter&utm_campaign=SHR_ARTT_20191008&utm_content=ondernemen#

[Bulder]

Yes, interesting that they don't rule out home administration in the future.

[Helge_LarsenPI-redaktør]

Så røg 1.350.

[Helge_LarsenPI-redaktør]

Ser dog ikke specielt overbevisende ud.

[Joakim_Von_And]

Gode tal i morgen vil nok kunne ses på omsætning sidst på dagen ,, Nogen kender jo tallene.....

[Sukkeralf]

Hvilke tal tænker du på ?

[Joakim_Von_And]

jnj tal

[polle1]

Først næste tirsdag !

[Sukkeralf]

yes 15 oktober

[Joakim_Von_And]

Så undskyld , jeg er Åbenbart en uge foran i mit hovede , var sikker på at det var denne onsdag... så må jeg hellere vente en uge mere

[nohope]

Tidligere var der en offentlig statistik der viste besøgstal på især mediehjemmesider, men den er ikke opdateret siden 2013. Jeg er nysgerrig efter udviklingen i besøg hos Euroinvestor -

[nohope]

Jeg ved godt at det ikke er Genmab relevant, og lover at jeg aldrig nogensinde vil skrive noget der ikke er Genmab relevant her.

[E_L]

Lazertinib in patients with..... non-small-cell lung cancer... https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(19)30504-2/fulltext

[Helge_LarsenPI-redaktør]

nohope..Vi kan tage den over mail. [email protected]

[E_L]

DNA methyltransferase inhibitors upregulate CD38 protein expression and enhance daratumumab efficacy in multiple myeloma - https://www.nature.com/articles/s41375-019-0587-5

[peter12]

@EL Could you give us the short version
?

[E_L]

another study to upregulate/enhance CD38 expression, like we saw with ATRA and Panobinostat. daratumumab targets CD38, but during treatment there is loss of CD38 expression on the MM cells.

[E_L]

If you can controll that back up, you could improve dara activity or even try to make dara work again in patients that have become resistant

[peter12]

So another pill will do it