Genmab — Oktober 2019
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Ikke desto mindre er Rev dominerende vedligeholdelsesbehandling i dag. Og lige blevet godkendt her i DK efter hårde sværdslag. Men selvfølgelig ophører det, når det ikke længere virker. Rev har også sine bivirkninger (Rev-belly kalder amerikanerne det - vi ville sige tyndskid) og det er ikke populært i det lange løb. Men for dem der ikke lider under det har Rev fordelen ved at være i pilleform.
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Der er også et dara+Rev vs Rev maintenance https://ir.genmab.com/news-releases/news-release-details/genmab-announces-phase-iii-study-exploring-daratumumab/
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Er dette konkurrence for dara + CyBorD i Amyloidosis? https://twitter.com/slentzsch/status/1180297578166079495?s=21
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Trump ser fjender alle steder. God morgen. :-). https://www.fiercepharma.com/pharma/without-evidence-trump-says-pharma-industry-could-be-behind-impeachment?mkt_tok=eyJpIjoiWmpsbFpUVTJNRFZpTjJNeiIsInQiOiJPMXgwazA2ekpMaHNId2dDdElHS0J1b1wvbXUxWUZTbXRNVHNGZU1GK3dSUW1uUXd5THJBXC9ma3NXY05TXC9peE5xT2tjZ0ZLbmdSWm9WUXpQb0NRU2plWTEwa2xqME1aSThPZVNXSEFhT3VHV0tsb2FpZUNpeDMwR29BRjNOMjNFeiJ9&mrkid=41140432
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Måske ny behandlings mulighed i MS. https://m.firstwordpharma.com/diabetes-drug-offers-hope-new-treatment-multiple-sclerosis
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Her uden noget login https://www.dailymail.co.uk/health/article-7536823/Type-2-diabetes-drug-offer-hope-multiple-sclerosis-study-rats.html Lidt vej endnu.
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Apropos snakken i går om bivirkninger ved Revlimid, så fandt jeg denne artikel af Plesner, hvor han ikke omtaler diarre, men derimod forstoppelse. Det sidste er også almindeligt, men diarre står øverst på listen på Celgenes Revlimid-hjemmeside. https://netdoktor.dk/myelomatose/behandling.htm https://www.revlimid.com/mm-patient/about-revlimid/what-are-the-possible-side-effects/
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Paul Richardson: And basically, lenalidomide related diarrhea is I think
probably an under-appreciated problem. https://www.lls.org/sites/default/files/National/USA/Pdf/Slides_Transcipts/transcript_extended_qa_myeloma_1.6.17.pdf -
Men Brian Durie har hjælpen klar https://www.youtube.com/watch?v=waJspG1JmfI
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