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Genmab — Maj 2019

Planlagt Fastgjort Låst Flyttet Genmab
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  • BulderB Offline
    BulderB Offline
    Bulder
    wrote on sidst redigeret af
    #817

    Columba looks fine: significantly lower rate of IRRs. Median(!) duration of injection was 5 mins.

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    0
    • BulderB Offline
      BulderB Offline
      Bulder
      wrote on sidst redigeret af
      #818

      SC=home run

      1 Reply Last reply
      0
      • S Offline
        S Offline
        Sukkeralf
        wrote on sidst redigeret af
        #819

        Just a moment...

        favicon

        (www.firstwordpharma.com)

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        0
        • nohopeN Offline
          nohopeN Offline
          nohope
          wrote on sidst redigeret af
          #820

          3xpartial response - does it have any value at all then ?

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          0
          • SolsenS Offline
            SolsenS Offline
            Solsen
            wrote on sidst redigeret af
            #821

            Nordea regner med 8-12% royalty på JNJ duobodies. De overhørte JNJs session i går og ser dara sc i solide opstartet i 2020.

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            0
            • J Offline
              J Offline
              JohnW
              wrote on sidst redigeret af
              #822

              dara sc i solide?

              1 Reply Last reply
              0
              • J Offline
                J Offline
                JohnW
                wrote on sidst redigeret af
                #823

                jeg troede dara i solide var lagt på hylden.

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                0
                • BulderB Offline
                  BulderB Offline
                  Bulder
                  wrote on sidst redigeret af
                  #824

                  vist en tanketorsk 😉

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                  0
                  • BulderB Offline
                    BulderB Offline
                    Bulder
                    wrote on sidst redigeret af
                    #825

                    isa IV er noget hurtigere end IV dara

                    1 Reply Last reply
                    0
                    • G Offline
                      G Offline
                      gentogen
                      wrote on sidst redigeret af
                      #826

                      Tak for info Sukkeralf (8.02)

                      1 Reply Last reply
                      0
                      • S Offline
                        S Offline
                        Sukkeralf
                        wrote on sidst redigeret af
                        #827

                        Solsen - lidt det Jan har sagt før, at når sc dosering er på plads i MM ville man måske forsøge igen

                        1 Reply Last reply
                        0
                        • SolsenS Offline
                          SolsenS Offline
                          Solsen
                          wrote on sidst redigeret af
                          #828

                          Nordea skriver at det har noget med bivirkningerne at gøre. Altså at sc er bedre at give sammen med steroider, hvis jeg forstår rigtigt.

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                          0
                          • S Offline
                            S Offline
                            Sukkeralf
                            wrote on sidst redigeret af
                            #829

                            Ja nok mindre brug for steroider når mængden af infusionsreaktioner er væsentlig mindre ved sc end iv

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                            0
                            • J Offline
                              J Offline
                              JohnW
                              wrote on sidst redigeret af
                              #830

                              Ok, så det er korrekt forstået at vi taler om Dara SC imod solide tumorer?

                              1 Reply Last reply
                              0
                              • BulderB Offline
                                BulderB Offline
                                Bulder
                                wrote on sidst redigeret af
                                #831

                                Undskyld solsen, ingen tanketorsk!. JnJ taler faktisk om at genoplive sc dara i solide.

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                                0
                                • S Offline
                                  S Offline
                                  Sukkeralf
                                  wrote on sidst redigeret af
                                  #832

                                  Kunne de så ikke også lige komme ud over stepperne i RA ligeså

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                                  0
                                  • E Offline
                                    E Offline
                                    E_L
                                    wrote on sidst redigeret af
                                    #833

                                    JNJ-61186372 (JNJ-372), an EGFR-cMet bispecific antibody, in EGFR-driven advanced non-small cell lung cancer (NSCLC). http://abstracts.asco.org/239/AbstView_239_247207.html

                                    1 Reply Last reply
                                    0
                                    • E Offline
                                      E Offline
                                      E_L
                                      wrote on sidst redigeret af
                                      #834

                                      Bryan Garnier
                                      "Isatuximab is not better than Darzalex

                                      Detailed results of ICARIA-MM study to be presented at ASCO
                                      Good results but not better than with Darzalex
                                      Darzalex will benefit from the subcutaneous administration
                                      We reduce our forecasts for isatuximab"

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                                      0
                                      • BulderB Offline
                                        BulderB Offline
                                        Bulder
                                        wrote on sidst redigeret af
                                        #835

                                        Kunne være særdeles interessant med en dara-bcmaxcd3 duobody kombo. Ren in house.

                                        1 Reply Last reply
                                        0
                                        • E Offline
                                          E Offline
                                          E_L
                                          wrote on sidst redigeret af
                                          #836

                                          the JNJ ASCO press release also mentions the Investigational Bispecific JNJ-61186372 (and offcourse Dara ) https://www.jnj.com/janssen-to-present-data-from-robust-oncology-portfolio-and-pipeline-at-the-2019-asco-annual-meeting-including-best-of-asco-selections

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