Genmab — Marts 2019
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Jeg synes egentlig dagen er fuld af lyspunkter.... i går kom superfine recepttal og GEN steg efterfølgende pænt. DEN markedsreaktion viser at markedsdeltagerne - trods alt - godt kan forstå at vi er trygt på vej.. way henover guidance for 2019! Det faktum giver mig glimmer for øjnene i ugevis
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God morgen.
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GSK / BCMA drug med gode resultater. https://m.firstwordpharma.com/glaxosmithkline-targets-regulatory-filings-year-end-anti-bcma-drug-gsk2857916-multiple-myeloma
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"
Meanwhile, among Darzalex-experienced patients, the drugmaker said the ORR and median PFS were 38.5 percent and 7.9 months, respectively. GlaxoSmithKline noted that no new safety signals were observed in the study". -
"And what is also encouraging is that Janssen recently, they also have a BCMA CD3 bispecific program using our DuoBody technology….& said in the business update that they intend to actually combine their BCMA CD3 bispecific together with daratumumab and not compete with daratumumab, and that is probably the right thing to do also for the BCMA ADC from Glaxo and potentially for Amgen's BCMA BiTE molecule."
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Tak for reminderen E L.
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Lidt svært helt at gennemskue, men 54% af patienterne var "Stage I" og alle ECOG 0 eller 1 (70% 1). Tidligere behandlinger fra 1 til over 10. 14 en eller anden slags Dara behandling tidligere. Safety lidt svær at vurdere da procenterne er procenter af alle, selv om kun 22 af 35 gennemførte (så tallene kan være for små - måske). De fremhæver selv at dette er det hidtil bedste, der er set efter Dara
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Genmab Announces European Regulatory Submission for Daratumumab in Combination with Lenalidomide and Dexamethasone in Frontline Multiple Myeloma
Company Announcement Type II variation application submitted to the EMA for daratumumab in combination with lenalidomide and dexamethasone as treatment...
GlobeNewswire News Room (www.globenewswire.com)
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