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Genmab — Februar 2019

Planlagt Fastgjort Låst Flyttet Genmab
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  • BulderB Offline
    BulderB Offline
    Bulder
    wrote on sidst redigeret af
    #620

    More: Limitations of this phase 1–2 open-label study include a
    small sample size in some tumour types and the absence
    of overall survival as a prespecified endpoint.

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    0
    • BulderB Offline
      BulderB Offline
      Bulder
      wrote on sidst redigeret af
      #621

      Several studies are underway,
      including InnovaTV 207 and InnovaTV 204. InnovaTV 207
      (NCT03485209) is an ongoing phase 2 study evaluating
      the activity, safety, and tolerability of tisotumab vedotin
      monotherapy administered every 3 weeks in patients
      with relapsed, locally advanced or metastatic colorectal
      cancer, squamous non-small-cell lung cancer, pancreatic
      cancer, or squamous cell carcinoma of the head and
      neck.

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      0
      • BulderB Offline
        BulderB Offline
        Bulder
        wrote on sidst redigeret af
        #622

        Following on from the encouraging preliminary activity seen in the cervical cancer cohort in this
        study, InnovaTV 204 (NCT03438396) is an ongoing
        phase 2 study evaluating the activity, safety, and
        tolerability of tisotumab vedotin monotherapy in patients
        with recurrent or metastatic cervical cancer that had
        progressed during or after treatment with standard firstline therapy.

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        • BulderB Offline
          BulderB Offline
          Bulder
          wrote on sidst redigeret af
          #623

          So the resonserates mentioned are not final, but must be confirmed in follow up studies.

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          • BulderB Offline
            BulderB Offline
            Bulder
            wrote on sidst redigeret af
            #624

            @ Pensionisten: Så det videre forløb er InnovaTV 204 og 207, som skal bekræfte data.

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            • E Offline
              E Offline
              E_L
              wrote on sidst redigeret af
              #625

              great, thanks @Bulder (- i only have the summary article so far)

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              • BulderB Offline
                BulderB Offline
                Bulder
                wrote on sidst redigeret af
                #626

                Maybe a little dangerous of de Bono to go to the press with these preliminary data. On the other hand, when a scientist does this he must be on safe ground.

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                • E Offline
                  E Offline
                  E_L
                  wrote on sidst redigeret af
                  #627

                  the feeling I got was that, maybe, he (or his sponsors...?) felt more data should have been disclosed as the lancet did, so he opened up a bit more?

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                  • H Offline
                    H Offline
                    Hamming
                    wrote on sidst redigeret af
                    #628

                    Iovance er data i Cervical er heller ikke helt off.

                    1 Reply Last reply
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                    • H Offline
                      H Offline
                      Hamming
                      wrote on sidst redigeret af
                      #629

                      https://twitter.com/bradloncar/status/1093911168060669952

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                      • BulderB Offline
                        BulderB Offline
                        Bulder
                        wrote on sidst redigeret af
                        #630

                        Sjovt de lige rammer 27%

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                        0
                        • P Offline
                          P Offline
                          peter12
                          wrote on sidst redigeret af
                          #631

                          Man skal passe meget på når N=15 😉

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                          • P Offline
                            P Offline
                            peter12
                            wrote on sidst redigeret af
                            #632

                            Og det samme gælder selvfølgelig Genmabs forsøg

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                            0
                            • B Offline
                              B Offline
                              bibob
                              wrote on sidst redigeret af
                              #633

                              @bulder 10.26. Kunne man tænke sig at at Novos tek. ang. Pilleform kunne overføres til Dara og Tiso qua deres samarbejde i kulissen. Det kunne jo være at der var et eller andet i gang som ikke kommer frem før der er sat noget i gang. ??. Når sc Dara kommer er det jo fremragende, -men hvis de kunne lave en oral version. Game over. 🙂

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                              • P Offline
                                P Offline
                                peter12
                                wrote on sidst redigeret af
                                #634

                                Lidt om Morphosys dommen
                                https://www.lw.com/mediaCoverage/litigators-of-the-week-latham-IP-litigators-kill-patent-challenge

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                                • StockBullS Offline
                                  StockBullS Offline
                                  StockBull
                                  wrote on sidst redigeret af
                                  #635

                                  Morn 🙂 fra Bangkok

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                                  • StockBullS Offline
                                    StockBullS Offline
                                    StockBull
                                    wrote on sidst redigeret af
                                    #636

                                    Ja Bibob kunne
                                    vaere fint hvis Genmab kunne faa patent paa en dara pille.

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                                    0
                                    • StockBullS Offline
                                      StockBullS Offline
                                      StockBull
                                      wrote on sidst redigeret af
                                      #637

                                      Eller en GT med dara -:)

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                                      • StockBullS Offline
                                        StockBullS Offline
                                        StockBull
                                        wrote on sidst redigeret af
                                        #638

                                        Ja hvıs vı smıder 500.000usd fra TV ovenı Dara of OFA for 2025 snakker vı kurs +4000 ved PE 25

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                                        0
                                        • StockBullS Offline
                                          StockBullS Offline
                                          StockBull
                                          wrote on sidst redigeret af
                                          #639

                                          Dara og OFA

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                                          0

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