Genmab — December 2018

GeorgeBest

Bekræfter at sc er bedre end iv

E_L

@Tandfeen-2 , the link works from here, can you search on twitter for this guy @NorthTxMSG ?

E_L

he also has poster 1995 https://twitter.com/NorthTxMSG/status/1069011970626469888 and 1996 https://twitter.com/NorthTxMSG/status/1069010197622927360

E_L

So Pollux median PFS 44.5 months

Solsen

vs 17,5 month with a HR at 0,44 - impressive.

Solsen

IRR 14% i sc vs ca 50% i iv also a very impressive improvement. The only concern is that the dara concentration in blood is reported at same level or HIGHER in sc 1800 mg vs 16 mg/kg in iv. But hopefully acceptable.

Tandfeen-2

Hvordan er blod koncentrationen ved 1200 mg?

Legolas23

Lidt stemningsoptakt til ASH https://youtu.be/ZKpeimQUAmY

Bulder

Ret bemærkelsesværdigt hvis det irske dara-cybord studie opviser samme mrd-neg som Griffin (50% ved end of consolidation).

Parasitism

https://twitter.com/apwiita/status/1069030959553503232?s=19

E_L

MedicalResearch.com Interview with:

Peter Voorhees, MD - CENTAURUS - https://medicalresearch.com/cancer-_-oncology/ash18-centaurus-study-evaluates-dosing-schedule-of-darzalex/46313/

E_L

and on Griffin https://www.onclive.com/conference-coverage/ash-2018/daratumumab-safe-and-effective-when-added-to-vrd-in-newly-diagnosed-mm

E_L

Despite interesting durable responses & low rates of infusion-related reactions $MOR s Anti-CD38 MOR202 will NOT be further developed in EU and US https://twitter.com/ThiloZander/status/1068972296281350144