Genmab — Oktober 2018
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Vedr CR-snakken i går aftes. I NEJM-artiklen fra 2014 er CR for Rd continuous på 15% (s. 909 øh). I Final analysis 21%. https://www.nejm.org/doi/pdf/10.1056/NEJMoa1402551 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5774211/
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I Alcyone havde D-VMp 42,6% sCR eller bedre. I Pollux havde D-Rd 42,3% sCR eller bedre. http://www.multiplemyelomahub.com/medical-information/ash-2017-phase-iii-alcyone-clinical-trial-daratumumab-plus-bortezomib-melphalan-and-prednisone-d-vmp-in-ndmm-patients-ineligible-for-transplant https://www.darzalexhcp.com/clinical-studies/pollux-efficacy
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snakker vi ikke en fordobing af en ubekendt?? Vi kender jo ikke CR i Rd armen. Det tal er vel også steget, når pfs er over 31mdr
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CR er ihvertfald ikke faldet, når nu Rd armen perfomer så godt
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Tossetime, og det er aldrig til at vide om AB ændrer retning i løbet af dagen.
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