Genmab — Oktober 2018

[Helge_LarsenPI-redaktør]

EL. I think most people have noticed that I'm making reminders around to ask questions many days before Q & A.

[E_L]

yeah… including me.. ahum… #guilty

[Helge_LarsenPI-redaktør]

[E_L]

Immunotherapy can fire up a protein that disables a T cell attack https://www.mdanderson.org/publications/cancer-frontline/2018/august-2018/immunotherapy-fires-up-protein-on-tumors-that-supresses-immune-a.html

[E_L]

i dont't want to fire up the dara/pd(l)1 debate again, but the article is from august

[E_L]

i only find 1 MD Anderson bladder cancer trial with dara , but this one does not have a pd1 https://clinicaltrials.gov/ct2/show/NCT03473730?term=cd38+bladder+Anderson&rank=1

[Bulder]

It must be a new study to come. Dara in solids still alive. Good easy to understand article that repeats what we've heard ealier from Limo Chen.

[Bulder]

Good sign that they (MD A.) hasn't given up the thought and is willing to finance a new study.

[Bulder]

Well, they don't say that the cd38-drug will be dara. It's my interpretation.

[E_L]

i searched for cd38, this was the only one and it was dara. Let's hope you are correct and it will still come.

[Bulder]

They also have the old one from last year in presurgical prostate. But again without pd1.

[peter12]

@EL You posted this link first time 28/8 but ok

[peter12]

What about this study ? https://www.clinicaltrialsregister.eu/ctr-search/search?query=nivolumab+daratumumab&dateFrom=2017-01-01&dateTo=2018-10-18

[Bulder]

Det første er MM. Det andet er et af BMS-studierne, som der skulle komme data fra om ikke så længe.

[E_L]

I just wanted to make sure you read it peter

[Bulder]

Samme som der her
https://www.clinicaltrials.gov/ct2/show/NCT03098550?term=daratumumab+nivolumab&rank=2

[peter12]

Remember its a dead cat

[E_L]

I don't want to be more optimistic as Jan, but i still have a bit of hope...

[Bulder]

No. only unconscious. And by the way a cat has 9 lives.

[peter12]

It must be breaking news