Genmab — Oktober 2018
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God morgen.
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POLLUX update Hematologia 20. sept...https://www.ncbi.nlm.nih.gov/pubmed/30237262
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51,2% CR og 92.9% ORR siger vidst alt
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CASTOR update Haematologica 20. sept ...free article...https://www.ncbi.nlm.nih.gov/pubmed/30237264
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Deutsche Bank: Forventer Darzalex salg på USD 563M for Q3 (Q2 var 511)
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The unique immunomodulatory characteristics of the CD38 target molecule and its downregulation by daratumumab-mediated trogocytosis may actually be one of the explanations that daratumumab is the first monoclonal antibody with single agent activity in MM..vdDong..https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154747/ ...fri artikel
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In the reported 3 patients with life-threatening posttransplant AIHA, daratumumab was curative in 2, with the third showing a transient response before relapse of AIHA 8 months after this therapy. The survivors are currently free of any signs of hemolysis with a follow-up of 18 and 13 months after administration of daratumumab....http://www.bloodadvances.org/content/2/19/2550.long?sso-checked=true
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Deutsche Bank mener at væksten i USA nu er nede på 3% (Q2 til Q3). Så hele væksten skal komme fra RoW. De mener ikke der vil være nogen nævneværdig 1. linie salg fra Europa....
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