Genmab — August 2018
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The FDA limited the use of two cancer drugs Merck’s Keytruda (pembrolizumab) and Roche’s Tecentriq (atezolizumab) and updated their labeling to reflect the new limitations.
The agency decided to restrict the drugs because of decreased survival associated with their use as monotherapies compared to platinum-based chemotherapy in clinical trials to treat metastatic urothelial cancer patients
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God morgen
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God morgen.
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God morgen
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Godmorgen, På gårsdagens Q&A svarede JVdW at Janssen er i gang med at teste DARA i raske frivillige inden der evt. opstartes studier i autoimmune sygdomme (RA). Hvad er det mere præcis man tester - eftersom mange patienter er behandlet kan det næppe være safety. Og virkning vel heller ikke da det er raske frivillige. ???
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Tolerability, Pharmacokinetics and Pharmacodynamics https://www.clinicaltrials.gov/ct2/show/NCT03320707?term=daratumumab+healthy&rank=1
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