Genmab — Juli 2018
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it is not good news, but not the end of the world. NICE has been playing the same game with Monotherapy. i would expect some sort of temporary solution with the Cancer Drugs Fund again at some point, until data is more mature (longer) and NICE will have to approve
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Det handler KUN om penge: " The committee agreed that the
improvements in progression-free survival with daratumumab plus
bortezomib and dexamethasone are large and that this combination is a
step-change in the treatment of people with multiple myeloma...... -
Og så videre: The committee
understood from patient and clinical experts, and the Cancer Drugs Fund
clinical lead, that an 18-month improvement in median progression-free
survival was considered a ‘game-changing’ treatment effect in the secondline
treatment of multiple myeloma. It concluded that daratumumab plus
bortezomib and dexamethasone had a statistically significant and clinically
important effect on progression-free survival compared with bortezomib
plus dexamethasone. -
@E L
Why is August 2nd important -
only because it is the Closing date for comments for this decision for NICE https://www.nice.org.uk/guidance/indevelopment/gid-ta10174/consultation/html-content-2
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"14.07" bedre anbefaling fås ikke.
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...men vi har da ikke nået pfs i de studier endnu?
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At AQR reducerer er vel også en positiv trigger.
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