Genmab — Juli 2018
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the Amgen and Immatics for comparison on size $$ https://immatics.com/press-release/amgen-immatics-enter-strategic-collaboration-develop-novel-bispecific-cancer-immunotherapies.html
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England’s cost effectiveness watchdog NICE has issued draft guidance not recommending Janssen's Darzalex (daratumumab) for second line use in multiple myeloma in combination with existing treatments. http://www.pmlive.com/pharma_news/daily_brief_trump_arrives_in_london,_nice_says_no_to_darzalex,_pfizer_backs_down_on_prices_1244070
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Well the 54M $ does not impact the income statement. But it must have impact on the cash balance.
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Trump heads to UK, to meet with pharma execs
The chief executives of Johnson & Johnson and GlaxoSmithKline are said to be attending a dinner with Trump and May.
Fox Business (www.foxbusiness.com)
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Dårligt nyt fra England. Burde kursen ikke falde på sådan en nyhed? Det er jo umiddelbart en stor potentiel gruppe som går tabt!
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it is not good news, but not the end of the world. NICE has been playing the same game with Monotherapy. i would expect some sort of temporary solution with the Cancer Drugs Fund again at some point, until data is more mature (longer) and NICE will have to approve
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Det handler KUN om penge: " The committee agreed that the
improvements in progression-free survival with daratumumab plus
bortezomib and dexamethasone are large and that this combination is a
step-change in the treatment of people with multiple myeloma...... -
Og så videre: The committee
understood from patient and clinical experts, and the Cancer Drugs Fund
clinical lead, that an 18-month improvement in median progression-free
survival was considered a ‘game-changing’ treatment effect in the secondline
treatment of multiple myeloma. It concluded that daratumumab plus
bortezomib and dexamethasone had a statistically significant and clinically
important effect on progression-free survival compared with bortezomib
plus dexamethasone. -
@E L
Why is August 2nd important -
only because it is the Closing date for comments for this decision for NICE https://www.nice.org.uk/guidance/indevelopment/gid-ta10174/consultation/html-content-2
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