Genmab — Juni 2018
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Ok. Lad os håbe at nogle af CAR-T
pengene kommer tilbage til Genmab. -
Barclays: Key takeaways from multiple myeloma physician dinner on BCMA CAR-T http://www.twitlonger.com/show/n_1sqi5um
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Bluebird og Genmab har iøvrigt exact samme markedsværdi. USD 9,15 milliarder. Sanseløst....
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CAR-T konceptet kan umuligt være en trussel for Dara.
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Helge - læs ELs link 22:01. Nogle mener car-t skal frem i behandlingsforløbet
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Har læst det, men jeg har svært ved at tro at det er muligt på det foreliggende grundlag.
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Hvis følger Twitter er det bestemt heller ikke konsensus at CAR-T skal frem. Langt de fleste mener det er super til de sene linier, men det er der det hører hjemme
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I linket fra E L hævdes det hele vejen igennem at BCMA CAR-T har en tilfredsstillede sikkerhedsprofil.
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Solsen se her: Interestingly enough, we found that this product is extremely well tolerated," said Raje. "We did see CRS in almost 60% of patients, but most of it was managed and it was grade 1 and 2 with very little grade 3 CRS, and we just had 1 patient with grade 4 neurotoxicity who is now completely recovered."
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Så jeg synes tolerabiliteten af CAR-T generelt for positiv kritik
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Tolerabiliteten er en ting. Det er mest det individuelle behandlingskoncept som virker for ressourcekrævende
i de første behandlingslinjer. -
I E L´s link hævedes det, at BCMA CAR-T eventuelt i nogen kan erstatte stamcelletransplantationer.
Efterbehandling kan så måske være Dara. -
tilfælde
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De glemmer da vist også lige det tidligere oplyste fra samme studie: There were two deaths in the active cohorts at 22 and 69 weeks following infusion, respectively. The first was due to cardiac arrest and the second was due to myelodysplastic syndrome; both subjects were in a myeloma CR at their last study assessment prior to death.
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Nu bliver der jo henvist til seneste data. Det du linket til er fra sidste år.
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Linker
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God morgen.
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