Genmab — Maj 2018

[Bulder]

He he, frankly speaking

[E_L]

Article in The Oncologist : Monoclonal Antibodies andMultipleMyeloma: All in All It’s Just
Another Brick in theWall? - http://theoncologist.alphamedpress.org/content/23/5/511.short?rss=1

• or the pdf : http://theoncologist.alphamedpress.org/content/23/5/511.full.pdf

[StockBull]

Ser frem til næste milestone. Mon vi høre fra Maria i Juni eller bliver det mon først i Juli der kommer data ?

[JKY_VH]

Maria kommer du nok til at vente længe på SB

[E_L]

[Bulder]

Der er skrevet en hel musical om Maria - the most beautiful sound I ever heard.

[StockBull]

Nå ja den der med Kim Larsen

[StockBull]

[StockBull]

Men det kan da godt være det først bliver i H2 vi får data fra Marie - for Jan har jo sådanset kun indikeret 2018 efter havd jeg kan se i.f.m Q1 Q&A

[Bulder]

Fra CC: "Around the summer this year, so early in the second half".

[E_L]

i previously tried to compare it to Alcyone, but that may be completely useless... Maia started 2 months later and had in the beginning a Dec18 completion date (vs 2021 Alcyone). That was extended a lot to 2022 and 2024 (primary dec2019). I am not sure why.

[Bulder]

Det tolker jeg som senest i løbet af august

[E_L]

Alcyone was fully recruited Dec16 and got unblinded Aug17 = 8 months. Maia was fully recruited Aug17 (+8 would be apr/may)

[Bulder]

But Revlimid is a much better drug than Velcade, so the control-arm performs better in Maia. That's why it takes longer to reach the median PFS in the control arm in Maia.

[E_L]

yes, that makes sense. And when they initiated the study in 2014 they probably did not know yet that Revlimid would perform that well?

[E_L]

meanwhile , Gilead will build its EU CAR-T manufacturing facility at Amsterdam airport https://www.fiercepharma.com/pharma/gilead-building-its-eu-car-t-manufacturing-amsterdam

[Mcjean]

If your smart E L you will open a bodybag store just beside

[E_L]

OMG Mcjean that is an awfull joke

[gentogen]

Maia var anført som fuldt rekrutteret i årsrapporten for 16 af 22-2-2017....

[Bulder]

Jeg tror, at når Genmab betegner studiet som fuldt rekrutteret, så mener de pts nok til at kunne udtrække data. Men på ct stod det som rekrutterende frem til aug. 17.