Genmab — Februar 2018

[gentogen]

A Study of Ixazomib+Daratumumab+Dexamethasone (IDd) in Relapsed and/or Refractory Multiple Myeloma (RRMM)

[gentogen]

ClinicalTrials.gov

(clinicaltrials.gov)

[E_L]

keep them coming gentogen

[Solsen]

Der kæmpes om resultater og omsætning. Jeg læser andet steds, at Revlimid og Pomalyst stiger voldsomt i pris.

[Solsen]

CELG kæmper så godt de kan for at fastholde deres position i MM.

[E_L]

true, but they have been succesfull so far fending of generics, Guess that is why they can keep prices moving up like crazy. https://www.bloomberg.com/news/features/2017-12-20/the-loopholes-drug-companies-use-to-keep-prices-high

[E_L]

whiich is a shame for Genmab offcourse as it makes the combo so expensive

[Solsen]

I think they try in short term to keep dara from the market as revlimid is more know and acceptet by now. To buy the combo is a hurdle for both pts and inssurance when CELG dramatically raise pricing.

[E_L]

I hadn't thought of that... do you know the price difference between Revlimid and Pomalidomide? Someone suggested the Dara/Pom/Dex combo could gain significance / compete
in the US based on price

[Solsen]

Read that pom are priced $200.000 annually.

[Solsen]

...and Revlimid $165.000 annually

[E_L]

ok, so that doesnt makes sense then...

[JohnW]

I guess a higher price on Revlimid will be an advantage for selling Alcyone then.

[Teller]

Hello, I am new to this chat, but I have been following it for more than a year now.

[Bulder]

Yes, or the US-equivalent to VMp: CyBorD

[Teller]

Maybe the higher price simply reflects a higher demand?

[Bulder]

The higher the Rev-price goes, the more important is the Dara+CyborD-study, from which we should see data soon.

[Teller]

Solsen - Hvilken dosis (stand alone eller combo) er denne aarlige behandlingspris baseret paa?

[E_L]

how much does
CyborD cost?

[Bulder]

The only drug of the three still patented is bor (Velcade), and it will run out of patent in Europe next year.