Genmab — Februar 2018
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BMY har lavet en del buzz omkring lung cancer behandling og deres checkmate studier. Er der nogen der har kigget nærmere på det. De referater jeg lige har skimmet taler om gennembrud og forståelse af hvordan man behandler lung cancer og måske flere typer cancer.
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@Solsen jeg har ikke dykket ned i data, men her er en kritisk vinkel på BMY checkmate 227 og anvendelsen af TMB (tumor mutation burden) https://www.marketwatch.com/story/bristol-myers-touts-lung-cancer-breakthrough-but-critics-cry-foul-2018-02-05?siteid=yhoof2&yptr=yahoo
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TMB diskuteres yderligere i BMY Earnings Call Transcript, både i starten og under Q&A https://seekingalpha.com/article/4143270-bristol-myers-squibbs-bmy-giovanni-caforio-q4-2017-results-earnings-call-transcript?part=single
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Mere om TMB, mulig markør for effektivitet af PD-1 / PD-L1 midler https://www.ncbi.nlm.nih.gov/pubmed/28835386
https://www.genengnews.com/gen-exclusives/the-promise-of-tumor-mutational-burden-for-cancer-immunotherapy/77900833 -
God morgen.
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