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Genmab — Januar 2018

Planlagt Fastgjort Låst Flyttet Genmab
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  • BulderB Offline
    BulderB Offline
    Bulder
    wrote on sidst redigeret af
    #1183

    Aner man en smule sarkasme GB? 🙂

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    • G Offline
      G Offline
      GeorgeBest
      wrote on sidst redigeret af
      #1184

      Nej jeg forstår det virkelig ikke. Hvis det kun er til de sene linier, er det jo en hel opskur pris. Og hvornår får de noget på markedet?

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      • G Offline
        G Offline
        GeorgeBest
        wrote on sidst redigeret af
        #1185

        Juno is currently recruiting for a phase 1 trial combining its BCMA-directed CAR-T therapy in combination with Revlimid, and has also just signed a licensing deal with Lilly on its myeloma CAR-T candidate. https://pharmaphorum.com/news/celgene-talks-buy-car-t-partner-juno/

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        • G Offline
          G Offline
          GeorgeBest
          wrote on sidst redigeret af
          #1186

          Phase 1???

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          • M Offline
            M Offline
            mobbyduck1
            wrote on sidst redigeret af
            #1187

            hvis de betaler omkring 10 mia USD er det præcist, hvad samtlige aktier i Genmab er værd pt. Det virker sgu da helt sygt, og som GB siger, hvornår begynder man at få skillinger i kassen, vel der kommer til at gå meget lang tid!

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            • G Offline
              G Offline
              GeorgeBest
              wrote on sidst redigeret af
              #1188

              Så kunne man
              også argumentere for at Humax-AXL-ADC skulle være så meget værd?

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              • M Offline
                M Offline
                Mcjean
                wrote on sidst redigeret af
                #1189

                Måske ved de og analytikerne noget om car-t vi ikke ved for de er da helt oppe at ringe over hvad der for mig ligner en sådan en her https://petrolicious.com/articles/a-humble-start-with-a-humble-trabant

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                • G Offline
                  G Offline
                  GeorgeBest
                  wrote on sidst redigeret af
                  #1190

                  Kan det være selve CAR-T teknologien de vil have? Den kan måske bruges i andre henseender?

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                  • J Offline
                    J Offline
                    JKY_VH
                    wrote on sidst redigeret af
                    #1191

                    😄 Mcj

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                    • G Offline
                      G Offline
                      GeorgeBest
                      wrote on sidst redigeret af
                      #1192

                      Indtægter fra 4-5 linie behandlinger kan ikke refærdiggøre det. Det same med Gilead der købte Kite for 12 mia USD...

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                      • nohopeN Offline
                        nohopeN Offline
                        nohope
                        wrote on sidst redigeret af
                        #1193

                        De må se mere I det end 4-5 linie.

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                        • S Offline
                          S Offline
                          Sukkeralf
                          wrote on sidst redigeret af
                          #1194

                          Det kunne være man skulle prøve at læse lidt om, hvad CAR-T selskaber selv mener det kan bruges til - og analytikere der følgeer disse selskaber

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                          • M Offline
                            M Offline
                            mobbyduck1
                            wrote on sidst redigeret af
                            #1195

                            JUNO er oppe med 53% i premarket og Bluebird oppe med 8%

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                            • E Offline
                              E Offline
                              E_L
                              wrote on sidst redigeret af
                              #1196

                              a bit more on NICE from MyelomaUK https://www.myeloma.org.uk/news/daratumumab-approved-for-use-on-the-nhs-in-england-and-wales/

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                              • S Offline
                                S Offline
                                Sukkeralf
                                wrote on sidst redigeret af
                                #1197

                                Indeed, Celgene made it a point at ASH to emphasise the speed at which the company and bluebird will be moving bb2121 forward. A pivotal trial (KarMMa) in late-stage patients will treat an initial patient this month, and the partners plan to start a Phase III trial next year in the third-line setting while simultaneously evaluating the product even further upstream, with a goal of moving into newly diagnosed patients

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                                • E Offline
                                  E Offline
                                  E_L
                                  wrote on sidst redigeret af
                                  #1198

                                  should still bring a minumum of €35mn in revenue
                                  in the UK this year, no?

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                                  • BulderB Offline
                                    BulderB Offline
                                    Bulder
                                    wrote on sidst redigeret af
                                    #1199

                                    mærkeligt at det er kun 4. linje og ikke 4. linje eller senere.

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                                    • E Offline
                                      E Offline
                                      E_L
                                      wrote on sidst redigeret af
                                      #1200

                                      yes... but it is correct according to p10 here https://www.england.nhs.uk/wp-content/uploads/2018/01/national-cdf-list-v1.59.pdf

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                                      • M Offline
                                        M Offline
                                        Mcjean
                                        wrote on sidst redigeret af
                                        #1201

                                        Maybe more than 35mn E L. If the first have open for treatment, maybe some patient can apply but i really dont know but im sure the analytics have to rise the estimate, maybe to 2.3 - 2.7?

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                                        • M Offline
                                          M Offline
                                          Mcjean
                                          wrote on sidst redigeret af
                                          #1202

                                          which will happen after 4q and that should result in higher rate, around 2000 i think:-)

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