Genmab — Januar 2018

[GeorgeBest]

OHW - nu ved vi jo at analytikere ikke vil tillægge prekliniske data nogen synderlig værdi! Så almindelig anerkendt er det først i deres verden når der er resultater fra klinikken

[E_L]

As of December 2016, there were at least eight other compounds in clinical or preclinical development that target AXL or its ligand....etc https://www.biocentury.com/bc-extra/preclinical-news/2018-01-15/combination-therapy-could-treat-tumors-resistant-mapk-pathway-?kwh="HuMax-AXL-ADC"

[OHW]

The researchers demonstrated that multiple types of AXL-high tumors can be effectively eliminated in this way.

[OHW]

..trods alt lidt af et statement.

[GeorgeBest]

AXL kan blive en rigtig gamechanger. Genmab ejer 100%, SGEN skal have single digit royalties, som kan udvikle sig til double digit.

[Mcjean]

.........and so it begins, a new blockbuster on its way..........tic tac

[Mcjean]

Pick a number, blue sky could be huge!

[Mcjean]

Hvad betyder en årlig merudgift på 500 mill. andet end at virksomheden straffes med en 12 mia kroners nedgang selvom de kan performe en ny blockbuster der får mærsk kurs inden split til at ligne lommepenge. Hvis det lykkedes vil NOVO ligne en bolsjebutik sammenlignet med Genmab.

[E_L]

according to this Genmab the only one -known- in the clinic with AXL target
http://worldadc-usa.com/wp-content/uploads/sites/99/2017/09/Heather-Donaghy.pdf

[E_L]

also thought this was funny page on ADCs

[E_L]

ADC Drug Map » ADC Review

ADC Drug Map » ADC Drug Map

ADC Review (adcreview.com)

[Mcjean]

first link error 403

[E_L]

strange, it works for me, can you try copy paste http://worldadc-usa.com/wp-content/uploads/sites/99/2017/09/Heather-Donaghy followed by .pdf

[E_L]

http:// worldadc-usa.com/wp-content/uploads/sites/99/2017/09/Heather-Donaghy .pdf

[E_L]

ok now you can see the link, take out the space at the beginning and end?

[Bulder]

Kunne se ud til at Genmab er den eneste med en AXL ADC i klinikken. På ct er der flere studier i axl-hæmmere. - Man må da i øvrigt sige at hollændernes opdagelse af de "røde og gule kugler" har fået pæn opmærksomhed.

[Bulder]

Multiple Myeloma Patients Remain On Treatment Far Less than in Clinical Trials, Study Finds https://myelomaresearchnews.com/2018/01/12/multiple-myeloma-patients-remain-on-treatment-less-than-clinical-trials-study-finds/?utm_source=Myeloma+List&utm_campaign=2a97d50a48-RSS_WEEKLY_EMAIL_CAMPAIGN&utm_medium=email&utm_term=0_14fcd0022a-2a97d50a48-72491777

[peter12]

Ved ikke om det er nyt ? http://pharma.nef2.com/global-pharma-market-will-reach-trillion-in-2022-pharmaceutical-commerce-global-pharma-global-pharma/

[E_L]

i think it is their 2016 report, they came with 2017 report last summer , so a bit outdated, then they forecasted 5.833bn for 2022 WW

[E_L]

by the way, in november they made a Dara projection for 2018 $1.932bn