Genmab — Oktober 2017

JørgenVarnæs

I hodgkin lymphoma. 8500 US patienter

JørgenVarnæs

Tf-adc cervical fase 2 kalder han approval trial...

JørgenVarnæs

...men retter sig selv til registration trial. Haha, hvad hjertet er fuld af

bibob

Sgen steg 6,51 % og J&J 2,02 % i går. Måske det smitter af på os idag.

GeorgeBest

Eli Lilly fejler senfasestudie med lungekræftkandidat http://medwatch.dk/Medicinal___Biotek/article9941299.ece?utm_campaign=Morgen&utm_content=2017-10-12 08%3A14%3A48&utm_medium=top&utm_source=Feed

E_L

i guess that must have been the first time Genmab was mentioned by Jim Cramer ; what a milestone lol

mobbyduck1

nope Genmab has been mentioned several time with darzalex/JNJ

Mcjean

E L i couldnt find out yesterday about Nice but since they have there own organisation in Skotland i think they cant get treatment there only if they pay. I saw on forums in England that people pay by them self........not cheap.

E_L

no Jim-Cramer-milestone payment
then

E_L

ok- hadnt seen any forums there, guess that confirms your thoughts Mcjean. Most people will not be able to afford that...

bibob

Er der nogen der har en ide om hvad der kan være årsagen til alle de suspend og withdrawn der er på dette studie med Dara i NSCLC. ? https://clinicaltrials.gov/ct2/show/NCT03023423?term=Darzalex&recrs=ab&cond=Nsclc&rank=1

GeorgeBest

Det har fremme tidligere. Problemet ligger hos Atezolizumab.

E_L

yea, but the one that was halted by the FDA was in MM, NCT02431208 . Should we
assume now they dont want to risk it in NSCLC either -for now?

bibob

It could be a big risk. Better stop and no results than continue and fail.

Sukkeralf

But still lots of locations are recruiting

Bulder

tror ikke det har noget med pd-1/pd-l1 problemet at gøre. Det var i kombi med iMids. Det er snarere in-/exclusions kriterierne der er stramme. Og så er der 104 lokationer og de skal bruge 96 pts. Så det går nok.

Bulder

Men at det lige præcis er de tyske lokationer der er suspenderede ser mystisk ud.

Sukkeralf

Lidt interesse for Selinexor:

Sukkeralf

(investors.karyopharm.com)

jkj

mere info om dara/nice og det nye combi forsøg i Englandhttps://pharmaphorum.com/news/myeloma-uk-launches-stratified-medicine-trial-darzalex-combo/