Genmab — December 2016
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It is amazing to see that we can get MRD negativity in the relapsed space. Both of these combinations were approved in November.
Noopur Raje, MD
Massachusetts General Hospital Cancer Center -
“Daratumumab led to rapid and durable achievement of MRD negativity,” Avet-Loiseau said. “Patients continue to achieve MRD negativity over time. The high rate of MRD negativity may lead to long-term clinical benefit. The magnitude of daratumumab-induced MRD negativity in the relapsed or refractory multiple myeloma setting is unprecedented.” – by Rob Volansky
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“MRD negativity was consistently higher in patients treated in daratumumab,” Avet-Loiseau said, adding that patients treated with the drug reached MRD negativity as soon as 3 months. “We still see patients achieving MRD negativity.”
High-risk patients also achieved MRD negative status in both studies, according to Avet-Loiseau. Eighteen percent of high-risk patients in the POLLUX study and 14% of those in CASTOR achieved MRD negativity.
“The most important factor in achieving PFS is MRD negati
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"unprecedented".
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Winkel lovede os flotte data på MRD negativitet på ASH. Det har vi så sandelig fået nu.
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Det må man sige.
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Minimal tilbageværende sygdom.
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Altså at patienten testes negativt for det.
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Det ligner et kæmpe nej i Italien, det kan godt give kraftige døninger i morgen! Desværre!
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Læs lige interview med Plesner igen - link fra Farfar1952 3/12 http://haematologisktidsskrift.dk/sygdomme/myeloma/222-daratumumab-rundt-pa-365-dage.html?user=al9hjgTY&passw=$2y$10$yNq10FjK8pizHgW/RWm.9O5hsjudYVck2.3tpOkerbTe4.Q8m7ecq
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