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Genmab — November 2014

Planlagt Fastgjort Låst Flyttet Genmab
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Denne tråd er blevet slettet. Kun brugere med emne behandlings privilegier kan se den.
  • S Offline
    S Offline
    Sukkeralf
    wrote on sidst redigeret af
    #159

    på Q&A

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    • G Offline
      G Offline
      gentogen
      wrote on sidst redigeret af
      #160

      The Committee recommended ofatumumab plus chlorambucil as a cost-effective use of NHS resources for untreated chronic lymphocytic leukaemia in people who are ineligible for fludarabine-based therapy, only if bendamustine is not suitable and the company provides ofatumumab with the discount agreed in the PAS.

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      • G Offline
        G Offline
        gentogen
        wrote on sidst redigeret af
        #161

        The Committee concluded that COMPLEMENT 1 showed that ofatumumab plus chlorambucil was more clinically effective than chlorambucil alone, as evidenced by statistically significantly longer progression-free survival and higher overall response rates.

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        • G Offline
          G Offline
          gentogen
          wrote on sidst redigeret af
          #162

          The Department of Health and the manufacturer have agreed that ofatumumab will be available to the NHS with a patient access scheme which makes ofatumumab available with a discount. The size of the discount is commercial in confidence.

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          • G Offline
            G Offline
            gentogen
            wrote on sidst redigeret af
            #163

            Link Preview Image
            Homepage

            NICE helps practitioners and commissioners get the best care to patients, fast, while ensuring value for the taxpayer

            favicon

            NICE website: The National Institute for Health and Care Excellence (www.nice.org.uk)

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            • G Offline
              G Offline
              gentogen
              wrote on sidst redigeret af
              #164

              NICE holder møde om dette igen i januar 2015

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              • Legolas23L Offline
                Legolas23L Offline
                Legolas23
                wrote on sidst redigeret af
                #165

                Mon ikke vi får "angrebet" på kurs 270 i dag ?

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                • L Offline
                  L Offline
                  lom
                  wrote on sidst redigeret af
                  #166

                  enig...26
                  8,5 nu

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                  • investor1989I Offline
                    investor1989I Offline
                    investor1989
                    wrote on sidst redigeret af
                    #167

                    De statistikker jeg har set svarer UK medicinalmarkedet til ca. 3-5% af det globale medicinalsalg.

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                    • investor1989I Offline
                      investor1989I Offline
                      investor1989
                      wrote on sidst redigeret af
                      #168

                      Så kan arzerra tage størstedelen af det marked vil de selv med en rabat kunne give et OK salg. Estimerer vi Rituxan sælger for 2 mia. $ alene i CLL worldwide bør UK udgøre knap 80 mia. $

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                      • S Offline
                        S Offline
                        Sukkeralf
                        wrote on sidst redigeret af
                        #169

                        Jo men de 80 millioner $ i CLL dækker jo alle linie-behandlinger hvor firstline i kombination med Chlorambucil kun er en del af dette.

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                        • S Offline
                          S Offline
                          Sukkeralf
                          wrote on sidst redigeret af
                          #170

                          Da NICE er meget strikse, så ligger der vel en ret god signalværdi i dette for hele Europa, så med en evt kommende godkendelse med Ofatumumab plus Fludarabine, så dækker man pludselig størstedelen af first line - og holder man prisen nede samt får Novartis på banen, så begynder det måske at ligne et mere seriøst angreb på markedsandele. Tillige har vi så Idelalisib + Ofatumumab i 2. linie - hvis data som forventet er gode.

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                          • S Offline
                            S Offline
                            Sukkeralf
                            wrote on sidst redigeret af
                            #171

                            Og maintenance lurer jo også - selv om jeg stadig er lidt tvivlsom på dette, men hvis man også her sætter prisen ned, så øges mulighederne jo for accept.

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                            • R Offline
                              R Offline
                              Repsac
                              wrote on sidst redigeret af
                              #172

                              Det går da galt for FF hvis han nu også skal komme Arzerra ind i hans formel

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                              • S Offline
                                S Offline
                                Sukkeralf
                                wrote on sidst redigeret af
                                #173

                                Upside risikoen er for alvor ved at udfolde sig !!

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                                • R Offline
                                  R Offline
                                  Repsac
                                  wrote on sidst redigeret af
                                  #174

                                  🙂

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                                  • R Offline
                                    R Offline
                                    Repsac
                                    wrote on sidst redigeret af
                                    #175

                                    Den kommentar havde jeg næsten glemt.

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                                    • SolsenS Offline
                                      SolsenS Offline
                                      Solsen
                                      wrote on sidst redigeret af
                                      #176

                                      Vi skal også huske at Roche er ved at gøre sig upopulær mange steder pga prissætning og voldsom fremfærd overfor kunderne - vi kan se en mulig gamechanger for Arzerra, hvor firstline kunne skubbe godt på !

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                                      • SolsenS Offline
                                        SolsenS Offline
                                        Solsen
                                        wrote on sidst redigeret af
                                        #177

                                        Link Preview Image
                                        Hospitals Furious at Cancer Drug Price Hike

                                        Some of the nation’s hospitals are seriously ticked off at Genentech, the San Francisco biotech firm, for implementing a stealth price hike for three critical...

                                        favicon

                                        TIME (time.com)

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                                        • J Offline
                                          J Offline
                                          JKY_VH
                                          wrote on sidst redigeret af
                                          #178

                                          haha Repsac

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