Genmab — April 2014
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det er også mit bud, men vi er helt oppe imod målstregen lige nu - så den kan vel falde nårsomhelst!!!
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Comparison of CDC activity using rituximab and ofatumumab revealed that the cytotoxic activity of ofatumumab was significantly higher than that of rituximab. http://onlinelibrary.wiley.com/doi/10.1111/bjh.12857/full
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she was receiving ofatumumab, a humanized anti-CD20 monoclonal antibody approved by the Food and Drug Administration for the treatment of multidrug-resistant CLL, with efficacy against rituximab-resistant B-cell cancers.4 Therapy with ofatumumab produced a dramatic response in the patient's renal status
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A phase 2 trial confirmed comparable high activity and safety of the O-FC (ofatumumab/fludarabine/cyclophosphamide) regimen as frontline treatment of previously untreated CLL. Investigators are moving forward with this regimen using the 1000-mg dose of ofatumumab.
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