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Genmab — August 2013

Planlagt Fastgjort Låst Flyttet Genmab
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Denne tråd er blevet slettet. Kun brugere med emne behandlings privilegier kan se den.
  • 1 Offline
    1 Offline
    120281
    wrote on sidst redigeret af
    #657

    For the record, J&J's collaboration with Pharmacyclics along with its breakthrough designation for daratumumab gives it four breakthrough designations on two drugs.

    Read more: Novartis wins a record breakthrough therapy designation for orphan drug - FierceBiotech http://www.fiercebiotech.com/story/novartis-win-record-breakthrough-therapy-designation-orphan-drug/2013-08-20#ixzz2caMIVNW3
    Subscribe at FierceBiotech

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    • G Offline
      G Offline
      gentogen
      wrote on sidst redigeret af
      #658

      Treatment of RA patients with SC ofatumumab doses of 30 mg or higher resulted in profound and prolonged B cell depletion in blood. Single doses up to 60 mg were tolerated without glucocorticoid premedication.

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      • G Offline
        G Offline
        gentogen
        wrote on sidst redigeret af
        #659

        Just a moment...

        favicon

        (www.jrheum.org)

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        • G Offline
          G Offline
          gentogen
          wrote on sidst redigeret af
          #660

          The efficacy and toxicity of ofatumumab-based CIT compare favorably to our historical trials of rituximab-based CIT using an identical chemotherapy backbone (n = 64). Time to retreatment also appeared longer for ofatumumab-based CIT (free of retreatment at 24 months: 86% [95% confidence interval = 75-99] versus 68% [95% confidence interval = 56-81] for rituximab-based CIT).

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          • G Offline
            G Offline
            gentogen
            wrote on sidst redigeret af
            #661

            Previously untreated CLL patients in need of therapy received 6 cycles of CIT induction with pentostatin, cyclophosphamide, and ofatumumab (PCO) followed by response assessment.

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            • G Offline
              G Offline
              gentogen
              wrote on sidst redigeret af
              #662

              The overall response rate was 96% (46 of 48 patients), and the CR rate was 46% (22 of 48 patients

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              • G Offline
                G Offline
                gentogen
                wrote on sidst redigeret af
                #663

                Just a moment...

                favicon

                (onlinelibrary.wiley.com)

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                • 1 Offline
                  1 Offline
                  120281
                  wrote on sidst redigeret af
                  #664

                  Det er vel kun good news

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                  • D Offline
                    D Offline
                    deleted-user
                    wrote on sidst redigeret af
                    #665

                    det er da vildt gode news

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                    • G Offline
                      G Offline
                      gentogen
                      wrote on sidst redigeret af
                      #666

                      Det mere end antydes, at dette mindst er på niveau med FCR, så det er vel ikke så ringe

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                      • D Offline
                        D Offline
                        deleted-user
                        wrote on sidst redigeret af
                        #667

                        nej og man må sige at markedet ikke har høje tanker om at arzerra er på vej mod at blive en seriøs konkurrent mod rituxian

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                        • BønneB Offline
                          BønneB Offline
                          Bønne
                          wrote on sidst redigeret af
                          #668

                          Hi

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                          • BønneB Offline
                            BønneB Offline
                            Bønne
                            wrote on sidst redigeret af
                            #669

                            hmmm

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                            • G Offline
                              G Offline
                              gentogen
                              wrote on sidst redigeret af
                              #670

                              http://www.evaluategroup.com/Universal/View.aspx?type=Report&id={8C80816D-658A-4085-BA10-B579001800B0}&params=<PARAMS currencyId="0"><PARAM linkKind="1" name="abio 05/01" /></PARAMS>&more=true#&&_ViewArgs={"_EntityType"%3A0%2C"_Parameters"%3A{"_ContextData"%3A"{\"isEPVantage\"%3Atrue%2C\"percentage\"%3A-1%2C\"searchWords\"%3A\"\"%2C\"sectionID\"%3A\"\"%2C\"storyID\"%3A\"449804\"%

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                              • J Offline
                                J Offline
                                JKY_VH
                                wrote on sidst redigeret af
                                #671

                                Er der noget nyt i EP Vantage interviewet?

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                                • SolsenS Offline
                                  SolsenS Offline
                                  Solsen
                                  wrote on sidst redigeret af
                                  #672

                                  ..vi kan ikke bruge linket gentogen.

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                                  • J Offline
                                    J Offline
                                    JKY_VH
                                    wrote on sidst redigeret af
                                    #673

                                    Mon denne virker?

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                                    • J Offline
                                      J Offline
                                      JKY_VH
                                      wrote on sidst redigeret af
                                      #674

                                      http://www.evaluategroup.com/Universal/View.aspx?type=Report&id={8C80816D-658A-4085-BA10-B579001800B0}&params=<PARAMS currencyId="0"><PARAM linkKind="1" name="abio 05/01" /></PARAMS>&more=true#&&_ViewArgs=%7b%22_EntityType%22%3a0%2c%22_Parameters%22%3a%7b%22_ContextData%22%3a%22%7b%5c%22isEPVantage%5c%22%3atrue%2c%5c%22percentage%5c%22%3a-1%2c%5c%22searchWords%5c%22%3a%5c%22%5c%22%2c%5c%22sectionID%5c%22%3a%5c%22%5c%22%2c%5c%22storyID%5c%22%3a%5c%22450132%5c%22%2c%5c%22notSub%5c%22%3afalse%7d%22

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                                      • D Offline
                                        D Offline
                                        deleted-user
                                        wrote on sidst redigeret af
                                        #675

                                        ikke rigitigt, men det gør dagens milestone meddelelse

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                                        • MadsSkjernM Offline
                                          MadsSkjernM Offline
                                          MadsSkjern
                                          wrote on sidst redigeret af
                                          #676

                                          hvad med dette link: http://www.evaluategroup.com/Universal/View.aspx?type=Story&id=450132&isEPVantage=yes

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