Jeg fik i oevrigt ikke inkluderet disse to figurer herfra:

Lilly's SURPASS-2 results published in The New England Journal of Medicine show tirzepatide achieved superior A1C and body weight reductions compared to injectable semaglutide in adults with type 2 diabetes

Lilly's SURPASS-2 results published in The New England Journal of Medicine show tirzepatide achieved superior A1C and body weight reductions compared to injectable semaglutide in adults with type 2 diabetes

Tirzepatide led to superior A1C and body weight reductions from baseline compared to injectable semaglutide 1 mg in 40-week results from Eli Lilly and Company's (NYSE: LLY) SURPASS-2 clinical...

Press Release Archive (lilly.mediaroom.com)

Jeg kan ikke vedhaefte, men figurerne viser, at tirzepatid 5mg virker lidt bedre end semaglutid 1mg baade med hensyn til HbA1c, krops-vaegt og lipider. Men jeg er ikke helt overbevist, at dual-agonister er det nye sort frem for kombinations-produkter som eksempelvis "OW Sema + GIP" fra Novo Nordisk i fase 1. Novo Nordisk har da ogsaa forrige aar droppet deres duo- og tri-agonist-kandidater. Tirzepatid bliver sikkert godkendt af FDA, men jeg tror, at Tirzepatid i hoej grad ankommer for sent til ballet, og Novo kommer til at sidde relativt tungt paa GLP1-markedet mod baade diabetes og fedme i en aar-raekke.

Novo Nordisk shelves 2 obesity drugs, will seek semaglutide approval at year-end
https://www.spglobal.com/marketintelligence/en/news-insights/blog/ngl-revenues-surge-in-q2-economic-rebound-underway-lumens-dilemma

Her link til Lilly-studiet hos clinicaltrials.gov:
https://www.clinicaltrials.gov/ct2/show/NCT03987919