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  4. Genmab — April 2023

Genmab — April 2023

Planlagt Fastgjort Låst Flyttet Genmab
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  • BulderB Offline
    BulderB Offline
    Bulder
    wrote on sidst redigeret af
    #169

    Og perspektiverne i et hex38-lenalidomid konjugat er jo svimlende, hvis det her virker.

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    • G Offline
      G Offline
      gentogen
      wrote on sidst redigeret af
      #170

      De laver også denne: "In db/db mice and diabetic rhesus monkeys, TE-8105 could reduce elevated blood glucose for longer periods and at lower dosage than semaglutide" og "In diet-induced obese (DIO) mice, TE-8105 could reduce body weight more effectively than semaglutide in a q4d regimen

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      • G Offline
        G Offline
        gentogen
        wrote on sidst redigeret af
        #171

        Link Preview Image
        免疫功坊股份有限公司Immunwork

        Immunwork, Inc. located in Taipei, Taiwan was founded in October 2014.After a corporate reorganization in November 2019, Immunwork is now a wholly owned subsidiary of T-E Pharma Holding, incorporated in Cayman Island. Immunwork focuses on the research and development of a class of new drugs, which are created based on our proprietary “T-E pharmaceuticals” technology platform. The first group of new drugs is for treating several types of cancer, diabetes, obesity, fatty liver diseases, and pathological blood clots.

        favicon

        免疫功坊股份有限公司 IMMUNWORK (www.immunwork.com)

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        • S Offline
          S Offline
          Sukkeralf
          wrote on sidst redigeret af
          #172

          Lidt om ADC generelt

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          • S Offline
            S Offline
            Sukkeralf
            wrote on sidst redigeret af
            #173

            Link Preview Image
            The Clinical Landscape Of ADCs In 2023: Diverse Technologies, Narrow Target

            Antibody-drug conjugates (ADCs) are a type of targeted cancer therapy that combines the specificity of monoclonal antibodies with the potency of...

            favicon

            (www.clinicalleader.com)

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            • P Offline
              P Offline
              peter12
              wrote on sidst redigeret af
              #174

              De behøver så ikke at buge dara i den ADC
              😉

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              • SolsenS Offline
                SolsenS Offline
                Solsen
                wrote on sidst redigeret af
                #175

                Det er jo netop giftstoffet der ofte er problemet mht sideeffects. Men spændende at følge udviklingen og lad os håbe, at Genmab er med i front. Fantastisk for patienter hvis nævnte effekt kan opnås uden væsentlig forringelse af bivirkningerne.

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                • BulderB Offline
                  BulderB Offline
                  Bulder
                  wrote on sidst redigeret af
                  #176

                  Fandt dette: “ Lysis af celler foregår hos højere organismer som fx mennesket under indvirkning af komplementsystemet: I celler, der bliver angrebet af en virus eller en bakterie, dannes der via dette system porer i cellemembranen, der tillader vand at trænge ind i cellen, som herved sprænges.” https://denstoredanske.lex.dk/lysis

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                  • BulderB Offline
                    BulderB Offline
                    Bulder
                    wrote on sidst redigeret af
                    #177

                    I abstr som vi diskuterede før forårsager TE-1146 netop lysis. Det kunne pege på hex-38, som netop har aktivering af komplementsystemet, som sin stærke side.

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                    • BulderB Offline
                      BulderB Offline
                      Bulder
                      wrote on sidst redigeret af
                      #178

                      Abstr er i øvrigt late breaking på AACR, så nogen opsigt må det have vakt.

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                      • StockBullS Offline
                        StockBullS Offline
                        StockBull
                        wrote on sidst redigeret af
                        #179

                        USD på vej mod 6.5 https://www.linkedin.com/pulse/teknik-hjælper-jens-schjerning/?midToken=AQH9tRHGf_Xm-Q&midSig=2yXqGbG6E2GqI1&trk=eml-email_series_follow_newsletter_01-newsletter_hero_banner-0-open_on_linkedin_cta&trkEmail=eml-email_series_follow_newsletter_01-newsletter_hero_banner-0-open_on_linkedin_cta-null-13d6e0~lgj22fs9~7t-null-null&eid=13d6e0-lgj22fs9-7t

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                        • StockBullS Offline
                          StockBullS Offline
                          StockBull
                          wrote on sidst redigeret af
                          #180

                          TA ugekort ved at gå i køb som kunne indikere en længere optur på 3-5 mdr a la 2021 og 2022. Sender et kort når købssignalet kommer i løbet af April. Dag kortet gav jo købssignal 14 Marts så indtil vidre fin optur.

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                          • J Offline
                            J Offline
                            JKY_VH
                            wrote on sidst redigeret af
                            #181

                            Tak SB

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                            • P Offline
                              P Offline
                              ProinvestorNEWS
                              wrote on sidst redigeret af
                              #182

                              Merck & Co. agrees to buy Prometheus for $10.8 billion https://firstwordpharma.com/story/5728300

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                              • Helge_LarsenPI-redaktørH Offline
                                Helge_LarsenPI-redaktørH Offline
                                Helge_LarsenPI-redaktør
                                wrote on sidst redigeret af
                                #183

                                Godmorgen 🙂

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                                0
                                • S Offline
                                  S Offline
                                  Stroka
                                  wrote on sidst redigeret af
                                  #184

                                  God morgen. 🙂

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                                  0
                                  • B Offline
                                    B Offline
                                    bibob
                                    wrote on sidst redigeret af
                                    #185

                                    God morgen. 🙂

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                                    0
                                    • P Offline
                                      P Offline
                                      ProinvestorNEWS
                                      wrote on sidst redigeret af
                                      #186

                                      MorphoSys : Long-term Data Show Prolonged, Durable Responses In DLBCL Patients Treated With Monjuvi https://www.proinvestor.com/investornyt/968633/morphosys-long-term-data-show-prolonged-durable-responses-in-dlbcl-patients-treated-with-monjuvi

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                                      • P Offline
                                        P Offline
                                        Pensionisten
                                        wrote on sidst redigeret af
                                        #187

                                        Så rr det jo i morgen middag, vi får nye tal fra J&J.

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                                        0
                                        • DarvinD Offline
                                          DarvinD Offline
                                          Darvin
                                          wrote on sidst redigeret af
                                          #188

                                          Genmab and argenx Enter Partnership to Advance Antibody Therapies in Immunology and Oncology

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