Genmab — December 2022
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@Sukkeralf, er aftalen med Bolt ikke noget lignende ADC https://ir.genmab.com/news-releases/news-release-details/genmab-and-bolt-biotherapeutics-announce-oncology-research-and/
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Immune-stimulating Antibody Conjugate (ISAC)
The technical requirements of immune-stimulating antibody conjugate (ISAC) are very similar to ADC, except that the ISAC load is an innate immune agonist or modulator that enables the ability to convert cold tumors into immune hot tumors. Also, similar in function to tumor microenvironment activated drug conjugates (TMAC) in part, both achieve activation of immune killing and therapeutic sensitization by modulating immune stimulation and microenvironm -
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Godmorgen
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Tak Sukkeralf, så Genmab er med på ADC toget
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Christmas reading- Journal of Clinical Oncology- Epcoritamab, a Novel, Subcutaneous CD3xCD20 Bispecific T-Cell–Engaging Antibody, in Relapsed or Refractory Large B-Cell Lymphoma: Dose Expansion in a Phase I/II Trial - https://ascopubs.org/doi/pdf/10.1200/JCO.22.01725
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