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  4. Genmab — December 2021

Genmab — December 2021

Planlagt Fastgjort Låst Flyttet Genmab
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Denne tråd er blevet slettet. Kun brugere med emne behandlings privilegier kan se den.
  • BulderB Offline
    BulderB Offline
    Bulder
    wrote on sidst redigeret af
    #92

    They haven

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    0
    • BulderB Offline
      BulderB Offline
      Bulder
      wrote on sidst redigeret af
      #93

      t updated on this study since Sept 2. So accoeding to that it is still only Vejle and Karolinska recruiting.

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      0
      • E Offline
        E Offline
        E_L
        wrote on sidst redigeret af
        #94

        we saw with the epco R/R CLL trial only 7 patients were enrolled in about 7/8 months; i wouldn't be surprised if this is going with the same speed

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        • E Offline
          E Offline
          E_L
          wrote on sidst redigeret af
          #95

          'speed'
          not being the best choice of words here 😉

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          0
          • E Offline
            E Offline
            E_L
            wrote on sidst redigeret af
            #96

            https://www.fda.gov/drugs/resources-information-approved-drugs/fda-approves-darzalex-faspro-kyprolis-and-dexamethasone-multiple-myeloma

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            • E Offline
              E Offline
              E_L
              wrote on sidst redigeret af
              #97

              Dara Kyprolis combi
              approved

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              0
              • BulderB Offline
                BulderB Offline
                Bulder
                wrote on sidst redigeret af
                #98

                Nice

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                • Legolas23L Offline
                  Legolas23L Offline
                  Legolas23
                  wrote on sidst redigeret af
                  #99

                  Thumps up

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                  0
                  • S Offline
                    S Offline
                    Sukkeralf
                    wrote on sidst redigeret af
                    #100

                    Just a moment...

                    favicon

                    (firstwordpharma.com)

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                    0
                    • BulderB Offline
                      BulderB Offline
                      Bulder
                      wrote on sidst redigeret af
                      #101

                      Hvad handler det om sukkeralf?

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                      0
                      • Legolas23L Offline
                        Legolas23L Offline
                        Legolas23
                        wrote on sidst redigeret af
                        #102

                        Kan du sætte lidt prosa. Linket kræver medlemskab.

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                        0
                        • Helge_LarsenPI-redaktørH Offline
                          Helge_LarsenPI-redaktørH Offline
                          Helge_LarsenPI-redaktør
                          wrote on sidst redigeret af
                          #103

                          God morgen. 🙂

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                          0
                          • G Offline
                            G Offline
                            GeorgeBest
                            wrote on sidst redigeret af
                            #104

                            Denne onkolog undrer sig over hvorfor man overhovedet vil anvende CAR-T i MM, når man snart kan få Teclistamab som vil være „safer, better, easier and cheaper“ https://twitter.com/drpaulydesantis/status/1466262720127258625?s=21

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                            0
                            • S Offline
                              S Offline
                              Sukkeralf
                              wrote on sidst redigeret af
                              #105

                              Detailed results from Roche's POLARIX study are poised to be one of the highlights at next week's annual meeting of the American Society of Hematology (ASH).

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                              • S Offline
                                S Offline
                                Sukkeralf
                                wrote on sidst redigeret af
                                #106

                                Roche notes that POLARIX is the first positive DLBCL Phase III study in a curative setting for two decades. Furthermore, it has suggested that sales of Polivy could peak at around $2 billion if the antibody-drug conjugate (ADC) becomes established as a new standard of care in the first-line setting.

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                                • S Offline
                                  S Offline
                                  Sukkeralf
                                  wrote on sidst redigeret af
                                  #107

                                  In response to publication of the abstract, we snap-polled 43 oncologists, 56% of whom said the Polivy-based regimen looks superior to current standard of care based on PFS data alone.

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                                  • S Offline
                                    S Offline
                                    Sukkeralf
                                    wrote on sidst redigeret af
                                    #108

                                    35% says acceptable adverse effect profile and 51% says manageable

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                                    0
                                    • S Offline
                                      S Offline
                                      Sukkeralf
                                      wrote on sidst redigeret af
                                      #109

                                      Taking efficacy and safety into account, results from POLARIX were described by 44% of oncologists as clinically meaningful and by a further 40% as promising, suggestive that physicians still want to see further detailed results and ideally a survival benefit (despite DLBLC being a relatively slowly progressing disease).

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                                      • S Offline
                                        S Offline
                                        Sukkeralf
                                        wrote on sidst redigeret af
                                        #110

                                        And then they want to see OS data

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                                        0
                                        • S Offline
                                          S Offline
                                          Sukkeralf
                                          wrote on sidst redigeret af
                                          #111

                                          Regarding Genmabs DuoBody agreement with Janssen we maybe could get an idea of how backloaded the deal is by looking at Zymeworks deal with Janssen.

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