Genmab — Marts 2021

[E_L]

The Immunomodulatory Effect and Clinical Efficacy of Daratumumab in a Patient With Cold Agglutinin Disease https://www.frontiersin.org/articles/10.3389/fimmu.2021.649441/full

[E_L]

we had a similar article last year. still wondering if we will ever see Dara in autoimmune diseases... at some point we were still hoping for rheumatoid arthritis...

[Bulder]

Try ask Winkel about it

[E_L]

we asked before...he'll refer to JNJ... we need Helge to set up a Q&A with Alex Gorsky really, don't we. Then we can also complain to him about bringing on this absurd royalty dispute...

[Helge_LarsenPI-redaktør]

[E_L]

Italians a bit slow... The Italian Medicines Agency (AIFA) has approved the reimbursement of Darzalex (daratumumab) when used in combination with lenalidomide and dexamethasone or bortezomib, melphalan and prednisone for patients with multiple myeloma. https://www.eversana.com/2021/03/01/last-week-in-review-2-22-2021-2-26-2021/

[deleted-user]

I

[deleted-user]

I'll bet Alex Gorsky already is running an alias at PI

[E_L]

you think he is spying to find out at what level we want to sell to him?

[Helge_LarsenPI-redaktør]

[Bulder]

Stadig ingen SH-tal fra sidste uge, Helge?

[Doublo]

Ja Jørgen Varnæs der er ikke mange analytikere man kan stole på, de har ofte selv en interesse i den kurs de sætter, er mit indtryk. I det hele taget er der alt for mange profeter.

[Helge_LarsenPI-redaktør]

Desværre ikke Bulder.

[E_L]

Potent Preclinical Efficacy of DuoHexaBody-CD37 in B-Cell Malignancies https://journals.lww.com/hemasphere/Fulltext/2021/01000/Potent_Preclinical_Efficacy_of_DuoHexaBody_CD37_in.3.aspx

[E_L]

'the combination of DuoHexaBody-CD37 with ofatumumab significantly enhanced the tumor cell kill in an additive manner' as a reminder , from earningscall 'one of the obvious candidates, of course, is potentially epco to basically combine it with the CD37 type of antibody. Because CD37 and CD20 are co-expressed for many targets'

[E_L]

i can't read the article, but prostate cancer is a big market.... 'CD38 as a Novel Immunosuppressive Target in Prostate Cancer' https://www.sciencedirect.com/science/article/abs/pii/S0302283821001421?via%3Dihub

[Solsen]

Ja man bliver ved med at lege med tanken om dara og solid cancer https://www.hindawi.com/journals/jo/2021/6630295/

[JørgenVarnæs]

Har i hørt vittigheden om den dag, hvor US åbnede og GEN ikke faldt

[gdn55]

Det er en gammel vits

[gdn55]

Men sådan er livet jo over there, mange tror jo også stadigvæk på at der var en anden de
r vandt valget.